Syndecan-1 is a cell surface heparan sulfate proteoglycan that binds to many mediators of
disease pathogenesis. Through these molecular interactions, syndecan-1 can modulate …

Patient management in oncology increasingly relies on imaging for diagnosis, response
assessment, and follow-up. The clinical availability of combined functional/anatomical …

We demonstrate a physiological role for tumstatin, a cleavage fragment of the α3 chain of
type IV collagen (Col IVα3), which is present in the circulation. Mice with a genetic deletion …

Fibronectin is an extracellular matrix protein found only in vertebrate organisms containing
endothelium-lined vasculature and is required for cardiovascular development in fish and …

Angiogenesis, the formation of new blood vessels from preexisting vasculature, contributes
to the pathogenesis of many disorders, including ischemic diseases and cancer. Integrins …

Vascular development requires correct interactions among endothelial cells, pericytes and
surrounding cells. These interactions involve many cell adhesion interactions, including cell …

I never intended to work on cell adhesion. My involvement in this fascinating field for the past
30 years originated in a desire to find molecular differences between the surfaces of normal …

The supramolecular design of bioactive artificial extracellular matrices to control cell
behavior is of critical importance in cell therapies and cell assays. Most previous work in this …

CD97, a membrane protein expressed at high levels on inflammatory cells and some
carcinomas, is a member of the adhesion G protein–coupled receptor family, whose …

It is emerging that nanotopographical information can be used to induce osteogenesis from
mesenchymal stromal cells from the bone marrow, and it is hoped that this nanoscale …