Chronic wounds exhibit persistent inflammation with markedly delayed healing. The
significant burden of chronic wounds, which are often resistant to standard therapy, prompts …

Post-traumatic osteoarthritis of the ankle (PTOA) is frequently observed following a
debilitating consequence of intra-articular ankle fractures. Numerous risk factors contribute …

The adhesion of tendon and surrounding tissue is the most common complication after
repairing an injured tendon. The injured flexor tendons in zone II are frequently …

Objective miR-122 stimulates proliferation of growth plate chondrocytes whereas miR-451
stimulates terminal differentiation and matrix turnover. Here, we examined the potential of …

This study was designed to investigate how low-intensity pulsed ultrasound (LIPUS)
suppresses traumatic joint inflammation and thereafter affects the progression of …

Introduction. Intra‐articular fractures are the leading etiology for posttraumatic osteoarthritis
(PTOA) in the ankle. Elevation of proinflammatory cytokines following intra‐articular fracture …

Several studies have reported the pathophysiologic and molecular mechanisms responsible
for pulmonary arterial hypertension (PAH). However, the in situ evidence of collagen V (Col …

The treatment of syndesmotic injuries has been a subject of continued interest and debate
for more than 100 years. 1–6 There is increasing consensus that adequate treatment of …

Osteoarthritis (OA) is characterized by a chronic, progressive and irreversible degradation of
the joint surface associated with joint inflammation. The main etiology of ankle OA is post …

Critical-size bone defects after compound fractures, infection, or tumor resection are
challenging to treat. The same is true for fractures in patients with impaired bone healing …