The human upper respiratory tract (URT) offers a variety of niches for microbial colonization.
Local microbial communities are shaped by the different characteristics of the specific …

Parkinson's disease is a progressive neurodegenerative disease characterized by tremor
and bradykinesia and is a common neurologic ailment. Male sex and advancing age are …

For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …

Background: Olfactory dysfunction is an increasingly recognised condition, associated with
reduced quality of life and major health outcomes such as neurodegeneration and death …

Parkinson’s Disease and Its Management - PMC Back to Top Skip to main content NIH NLM
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Importance Parkinson disease is the second most common neurodegenerative disease
worldwide. Although no available therapies alter the underlying neurodegenerative process …

Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Parkinson's Disease (PD) is a neurodegenerative disorder that affects dopaminergic
neurons in the mesencephalic substantia nigra, causing a progressive clinical course …

Parkinson's disease (PD) is characterized by the progressive appearance of intraneuronal
Lewy aggregates, which are primarily composed of misfolded α-synuclein (α-syn). The …

Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …