Cytokines are involved in intestinal homeostasis and pathological processes associated
with inflammatory bowel disease (IBD). The biological effects of cytokines, including several …

Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

Imbalance of gut microbiota homeostasis is related to the occurrence of ulcerative colitis
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …

Catechins are natural polyphenolic phytochemicals that exist in food and medicinal plants,
such as tea, legume and rubiaceae. An increasing number of studies have associated the …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway
constitute the fulcrum in many vital cellular processes, including cell growth, differentiation …

Patients with chronic inflammatory bowel diseases are at an increased risk of developing
colitis-associated cancer (CAC). Chronic inflammation positively correlates with …

Background & Aims Altered levels and functions of microRNAs (miRs) have been associated
with inflammatory bowel diseases (IBDs), although little is known about their roles in …

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is
activated downstream of a broad range of receptors particularly interleukin-6 (IL-6) family …

Background Inflammation is an essential immune response; however, chronic inflammation
results in disease including Crohn's disease. Therefore, reducing the inflammation can yield …