The bacterial cell envelope
TJ Silhavy, D Kahne, S Walker - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The bacteria cell envelope is a complex multilayered structure that serves to protect these
organisms from their unpredictable and often hostile environment. The cell envelopes of …
organisms from their unpredictable and often hostile environment. The cell envelopes of …
Outer membrane biogenesis
A Konovalova, DE Kahne… - Annual review of …, 2017 - annualreviews.org
The hallmark of gram-negative bacteria and organelles such as mitochondria and
chloroplasts is the presence of an outer membrane. In bacteria such as Escherichia coli, the …
chloroplasts is the presence of an outer membrane. In bacteria such as Escherichia coli, the …
Prospects for new antibiotics: a molecule-centered perspective
CT Walsh, TA Wencewicz - The Journal of antibiotics, 2014 - nature.com
There is a continuous need for iterative cycles of antibiotic discovery and development to
deal with the selection of resistant pathogens that emerge as therapeutic application of an …
deal with the selection of resistant pathogens that emerge as therapeutic application of an …
Structural basis of outer membrane protein insertion by the BAM complex
Y Gu, H Li, H Dong, Y Zeng, Z Zhang, NG Paterson… - Nature, 2016 - nature.com
All Gram-negative bacteria, mitochondria and chloroplasts have outer membrane proteins
(OMPs) that perform many fundamental biological processes. The OMPs in Gram-negative …
(OMPs) that perform many fundamental biological processes. The OMPs in Gram-negative …
Importing mitochondrial proteins: machineries and mechanisms
Most mitochondrial proteins are synthesized on cytosolic ribosomes and must be imported
across one or both mitochondrial membranes. There is an amazingly versatile set of …
across one or both mitochondrial membranes. There is an amazingly versatile set of …
Structural insight into the biogenesis of β-barrel membrane proteins
Abstract β-barrel membrane proteins are essential for nutrient import, signalling, motility and
survival. In Gram-negative bacteria, the β-barrel assembly machinery (BAM) complex is …
survival. In Gram-negative bacteria, the β-barrel assembly machinery (BAM) complex is …
Outer membrane protein biogenesis in Gram-negative bacteria
SE Rollauer, MA Sooreshjani… - … Transactions of the …, 2015 - royalsocietypublishing.org
Gram-negative bacteria contain a double membrane which serves for both protection and for
providing nutrients for viability. The outermost of these membranes is called the outer …
providing nutrients for viability. The outermost of these membranes is called the outer …
Structure of a nascent membrane protein as it folds on the BAM complex
Mitochondria, chloroplasts and Gram-negative bacteria are encased in a double layer of
membranes. The outer membrane contains proteins with a β-barrel structure,. β-Barrels are …
membranes. The outer membrane contains proteins with a β-barrel structure,. β-Barrels are …
The structure of the β-barrel assembly machinery complex
J Bakelar, SK Buchanan, N Noinaj - Science, 2016 - science.org
β-Barrel outer membrane proteins (OMPs) are found in the outer membranes of Gram-
negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200 …
negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200 …
The β-barrel assembly machinery in motion
N Noinaj, JC Gumbart, SK Buchanan - Nature Reviews Microbiology, 2017 - nature.com
In Gram-negative bacteria, the biogenesis of β-barrel outer membrane proteins (OMPs) is
mediated by the β-barrel assembly machinery (BAM) complex. During the past decade …
mediated by the β-barrel assembly machinery (BAM) complex. During the past decade …