Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

The relation between acute ischaemic stroke and infection is complex. Infection appears to
be an important trigger that precedes up to a third of ischaemic strokes and can bring about …

Inflammation is a classical host defence response to infection and injury that has many
beneficial effects. However, inappropriate (in time, place and magnitude) inflammation is …

Neuroimmunology as a separate discipline has its roots in the fields of neurology,
neuroscience and immunology. Early studies of the brain by Golgi and Cajal, the detailed …

Ischemic stroke (IS) produces a powerful inflammatory cascade in the brain, resulting in the
occurrence of neuroinflammation. Neuroinflammation is triggered not only by resident …

Background and Purpose—Experimental studies have shown that hyperthermia is a
determinant of poor outcome after ischemic stroke. Clinical studies evaluating the effect of …

Background and Purpose—Muscle wasting is a common complication accompanying
stroke. Although it is known to impair poststroke recovery, the mechanisms of subacute …

Hyperglycemia affects approximately one-third of acute ischemic stroke patients and is
associated with poor clinical outcomes. In experimental and clinical stroke studies …

Background Although free radicals have been reported to play a role in the expansion of
ischemic brain lesions, the effect of free radical scavengers is still under debate. In this …

Background Early predictors for the development of stroke-associated infection may identify
patients at high risk and reduce post-stroke infection and mortality. Methods In 383 …