Navigating the landscape: Prospects and hurdles in targeting vascular smooth muscle cells for atherosclerosis diagnosis and therapy

J He, Y Gao, C Yang, Y Guo, L Liu, S Lu… - Journal of Controlled …, 2024 - Elsevier
Vascular smooth muscle cells (VSMCs) have emerged as pivotal contributors throughout all
phases of atherosclerotic plaque development, effectively dispelling prior underestimations …

Fluorinated MRI contrast agents and their versatile applications in the biomedical field

E Hequet, C Henoumont, RN Muller… - Future medicinal …, 2019 - Taylor & Francis
MRI has been recognized as one of the most applied medical imaging techniques in clinical
practice. However, the presence of background signal coming from water protons in …

Arterial inflammation in young patients with human immunodeficiency virus infection: a cross-sectional study using F-18 FDG PET/CT

IO Lawal, AO Ankrah, GO Popoola, T Lengana… - Journal of Nuclear …, 2019 - Elsevier
Background HIV infection is associated with the risk of development of atherosclerosis at a
younger age. We compared arterial inflammation in HIV-infected and HIV-uninfected …

[HTML][HTML] Arterial wall inflammation in rheumatoid arthritis is reduced by anti-inflammatory treatment

AB Blanken, R Agca, AM van Sijl, AE Voskuyl… - Seminars in arthritis and …, 2021 - Elsevier
Background Rheumatoid arthritis (RA) patients have an increased risk of cardiovascular
disease (CVD), partly due to an increased prevalence of cardiovascular risk factors, but also …

[18F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic Plaque Imaging

C De Dominicis, P Perrotta, S Dall'Angelo… - ACS Medicinal …, 2020 - ACS Publications
PFKFB3, a glycolysis-related enzyme upregulated in inflammatory conditions and
angiogenesis, is an emerging target for diagnosis and therapy of atherosclerosis. The …

Future growth and success of nuclear cardiology

GA Beller - Journal of Nuclear Cardiology, 2018 - Springer
About 6 months ago, I reviewed a manuscript, and subsequently wrote an editorial, 1
pertaining to a retrospective study undertaken by Mayo Clinic investigators, reporting a …

Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2017. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic …

WA AlJaroudi, FG Hage - Journal of Nuclear Cardiology, 2018 - Elsevier
Several original articles and editorials have been published in the Journal of Nuclear
Cardiology in 2017. It has become a tradition at the beginning of each year to summarize …

Molecular Imaging of Atheroma: Deciphering How and When to Use 18F-Sodium Fluoride and 18F-Fluorodeoxyglucose

A Tawakol, MT Osborne, ZA Fayad - Circulation: Cardiovascular …, 2017 - Am Heart Assoc
of active microcalcification within the atheroma. Vascular calcification has long been known
to associate with cardiovascular risk. Larger deposits of calcium can be detected with CT …

Synthesis and Evaluation of 11C- and 18F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents

JR Hill, X Shao, JS Wright, J Stauff… - ACS Medicinal …, 2020 - ACS Publications
PD-132301, an inhibitor of sterol O-acyltransferase 1 (SOAT1; also known as acyl-coenzyme
A: cholesterol acyltransferase-1, ACAT1), is under clinical investigation for numerous …

Emerging Preclinical and Clinical Applications of Theranostics for Nononcological Disorders

M Assadi, N Jokar, A Yordanova… - PET clinics, 2021 - pet.theclinics.com
Studies in nuclear medicine have shed light on molecular imaging and therapeutic
approaches for oncological and nononcological conditions. Theranostic approaches using …