High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

Major depressive disorder (MDD) has a high prevalence and is a major contributor to the
global burden of disease. This psychiatric disorder results from a complex interaction …

Exercise is increasingly recommended as a supportive therapy for people with Multiple
Sclerosis (pwMS). While clinical research has still not disclosed the real benefits of exercise …

The beneficial effects of exercise on human brain function have been demonstrated in
previous studies. Myokines secreted by muscle have attracted increasing attention because …

Depression is a common mental disorder in which patients often experience feelings of
sadness, fatigue, loss of interest, and pleasure. Exercise is a widely used intervention for …

Adaptive neuroplasticity is a pivotal mechanism for healthy brain development and
maintenance, as well as its restoration in disease-and age-associated decline. Management …

Exercise not only builds up our body but also improves cognitive function. Skeletal muscle
secretes myokine during exercise as a large reservoir of signaling molecules, which can be …

Single-factor intervention, such as physical exercise and auditory and visual stimulation,
plays a positive role on the prevention and treatment of Alzheimer's disease (AD); however …

Aerobic exercise promotes beneficial effects in the brain including increased synaptic
plasticity and neurogenesis and regulates neuroinflammation and stress response via the …

Vitamin D3 (cholecalciferol) has been shown to exert antidepressant-like responses, but the
role BDNF/TrkB-related synaptic plasticity in this effect remains to be established. Thus, this …