Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation
Inherited noncoding genetic variants confer significant disease susceptibility to childhood
acute lymphoblastic leukemia (ALL) but the molecular processes linking germline …
acute lymphoblastic leukemia (ALL) but the molecular processes linking germline …
Drug resistance biomarkers and their clinical applications in childhood acute lymphoblastic leukemia
N Aberuyi, S Rahgozar, ES Ghodousi… - Frontiers in oncology, 2020 - frontiersin.org
Biomarkers are biological molecules found in body fluids or tissues, which can be
considered as indications of a normal or abnormal process, or of a condition or disease …
considered as indications of a normal or abnormal process, or of a condition or disease …
[PDF][PDF] Philadelphia chromosome-like acute lymphoblastic leukemia: progress in a new cancer subtype
J Wells, N Jain, M Konopleva - Clin Adv Hematol …, 2017 - hematologyandoncology.net
Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia: Progress in a New Cancer
Subtype Page 1 554 Clinical Advances in Hematology & Oncology Volume 15, Issue 7 July 2017 …
Subtype Page 1 554 Clinical Advances in Hematology & Oncology Volume 15, Issue 7 July 2017 …
Philadelphia-like acute lymphoblastic leukemia: the journey from molecular background to the role of bone marrow transplant
Philadelphia chromosome-like (Ph-like) ALL is a recent subtype of acute lymphoblastic
leukemia. Although it does not express the BCR-ABL fusion gene, it has a behavior like true …
leukemia. Although it does not express the BCR-ABL fusion gene, it has a behavior like true …
Genetic variation of the transcription factor GATA3, not STAT4, is associated with the risk of type 2 diabetes in the Bangladeshi population
Type 2 diabetes mellitus is a multifactorial metabolic disorder caused by environmental
factors and has a strong association with hereditary issues. These hereditary issues result in …
factors and has a strong association with hereditary issues. These hereditary issues result in …
Concepts in B cell acute lymphoblastic leukemia pathogenesis
C Garcia, MD Miller-Awe, MT Witkowski - 2024 - academic.oup.com
B-cell acute lymphoblastic leukemia (B-ALL) arises from genetic alterations impacting B-cell
progenitors, ultimately leading to clinically overt disease. Extensive collaborative efforts in …
progenitors, ultimately leading to clinically overt disease. Extensive collaborative efforts in …
GATA3 germline variant is associated with CRLF2 expression and predicts outcome in pediatric B‐cell precursor acute lymphoblastic leukemia
The germline variant at rs3824662 in GATA3 is a risk locus for Philadelphia‐like acute
lymphoblastic leukemia (Ph‐like ALL), the biological subtype of B‐cell precursor (BCP)‐ALL …
lymphoblastic leukemia (Ph‐like ALL), the biological subtype of B‐cell precursor (BCP)‐ALL …
[HTML][HTML] Genes of Predisposition to Childhood Beta-Cell Acute Lymphoblastic Leukemia in the Kazakh Population
G Svyatova, R Boranbayeva, G Berezina… - Asian Pacific Journal …, 2023 - ncbi.nlm.nih.gov
Background: Today, acute lymphoblastic leukemia is one of the most common malignant
diseases of the hematopoietic system. The genetic predisposition to ALL is not fully explored …
diseases of the hematopoietic system. The genetic predisposition to ALL is not fully explored …
[HTML][HTML] Genetic Insights Into Leukemia Susceptibility in the Arab Population: A Scoping Review
A Algarni - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
As per the Global Cancer Observatory, the WHO Eastern Mediterranean region (which
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …
includes the Arabic countries) ranks highest for age-standardized mortality rate at 4 per …
GATA3 rs3824662 gene polymorphism as possible risk factor for systemic lupus erythematosus
Background There is no report about the association between GATA3 rs3824662
polymorphism and systemic lupus erythematosus (SLE). Objective To investigate the …
polymorphism and systemic lupus erythematosus (SLE). Objective To investigate the …