[HTML][HTML] Sulforaphane: A broccoli bioactive phytocompound with cancer preventive potential

AE Kaiser, M Baniasadi, D Giansiracusa… - Cancers, 2021 - mdpi.com
There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

[HTML][HTML] Epigenetics: a new bridge between nutrition and health

SW Choi, S Friso - Advances in nutrition, 2010 - Elsevier
Nutrients can reverse or change epigenetic phenomena such as DNA methylation and
histone modifications, thereby modifying the expression of critical genes associated with …

Review of natural compounds for potential skin cancer treatment

TN Chinembiri, LH Du Plessis, M Gerber, JH Hamman… - Molecules, 2014 - mdpi.com
Most anti-cancer drugs are derived from natural resources such as marine, microbial and
botanical sources. Cutaneous malignant melanoma is the most aggressive form of skin …

The role of isothiocyanates as cancer chemo-preventive, chemo-therapeutic and anti-melanoma agents

M Mitsiogianni, G Koutsidis, N Mavroudis, DT Trafalis… - Antioxidants, 2019 - mdpi.com
Many studies have shown evidence in support of the beneficial effects of phytochemicals in
preventing chronic diseases, including cancer. Among such phytochemicals, sulphur …

Sulforaphane as an anticancer molecule: Mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems

MM Kamal, S Akter, CN Lin, S Nazzal - Archives of pharmacal research, 2020 - Springer
Sulforaphane is an isothiocyanate compound that has been derived from cruciferous
vegetables. It was shown in numerous studies to be active against multiple cancer types …

Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane

L Yang, DL Palliyaguru, TW Kensler - Seminars in oncology, 2016 - Elsevier
With the properties of efficacy, safety, tolerability, practicability and low cost, foods containing
bioactive phytochemicals are gaining significant attention as elements of chemoprevention …

Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review

S Khan, KA Awan, MJ Iqbal - Journal of Food biochemistry, 2022 - Wiley Online Library
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various
biological benefits for health promotion and disease prevention. This compound is …

[HTML][HTML] Regulation of immunomodulatory networks by Nrf2-activation in immune cells: Redox control and therapeutic potential in inflammatory diseases

T Pant, N Uche, M Juric, J Zielonka, X Bai - Redox Biology, 2024 - Elsevier
Inflammatory diseases present a serious health challenge due to their widespread
prevalence and the severe impact on patients' lives. In the quest to alleviate the burden of …

A review on phase-inversion technique-based polymer microsphere fabrication

SL Duraikkannu, R Castro-Muñoz, A Figoli - Colloid and Interface Science …, 2021 - Elsevier
In this review, the preparation method of polymer microspheres (MCs) by phase-inversion is
addressed and discussed in detail. An interesting advantage of MCs prepared by the PI …

Combinations of the antioxidants sulforaphane or curcumin and the conventional antineoplastics cisplatin or doxorubicin as prospects for anticancer chemotherapy

M Negrette-Guzman - European journal of pharmacology, 2019 - Elsevier
Drugs used in clinical oncology have narrow therapeutic indices with adverse toxicity often
involving oxidative damage. Chemoresistance to these conventional antineoplastics is …