Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …

This comprehensive practice parameter for allergic rhinitis (AR) and nonallergic rhinitis
(NAR) provides updated guidance on diagnosis, assessment, selection of monotherapy and …

CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary …

The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex
and expensive, tests. In many cases, however, the diagnosis remains difficult despite the …

Primary ciliary dyskinesia is a genetically and clinically heterogeneous syndrome. Impaired
function of motile cilia causes failure of mucociliary clearance. Patients typically present with …

Symptoms of primary ciliary dyskinesia (PCD) are nonspecific and guidance on whom to
refer for testing is limited. Diagnostic tests for PCD are highly specialised, requiring …

Dysfunction of motile monocilia, altering the leftward flow at the embryonic node essential for
determination of left-right body asymmetry, is a major cause of laterality defects. Laterality …

Background Diagnosis of primary ciliary dyskinesia (PCD) relies on a combination of tests.
High-speed video microscopy analysis (HSVA) is widely used to contribute to the diagnosis …

Nitric oxide is continually synthesised in the respiratory epithelium and is upregulated in
response to infection or inflammation. Primary ciliary dyskinesia (PCD) is characterised by …

Primary ciliary dyskinesia is a genetically heterogeneous disorder of motile cilia that is
predominantly inherited in an autosomal-recessive fashion. It is associated with abnormal …