Diabetes mellitus is a multifactorial disease, classically influenced by genetic determinants
of individual susceptibility and by environmental accelerating factors, such as lifestyle. It is …

Diabetes mellitus represents a major risk factor for the development of coronary artery
disease and other vascular complications. Glycated haemoglobin, fructosamine, and fasting …

Hemoglobin HbA1c (A1c) has been used clinically since the 1980s as a test of glycemic
control in individuals with diabetes. The Diabetes Control and Complications Trial (DCCT) …

Hare MJL, Shaw JE, Zimmet PZ (Baker IDI Heart and Diabetes Institute, Melbourne, Vic.; and
Monash University, Melbourne, Vic.; Australia). Current controversies in the use of …

Post-translational modifications (PTMs) of proteins and peptides have recently gained much
attention, as they are involved in the pathogenesis of cardiovascular disease and eventually …

Background Although measurement of haemoglobin A1c has become the cornerstone for
diagnosing diabetes mellitus in routine clinical practice, the role of this biomarker in …

A 12-week feeding trial was performed to evaluate the effects of metformin on growth
performance, energy sensing, insulin signaling pathway, glycolipid metabolism and glucose …

Humanity is facing a diabetes epidemic with uncontrolled progress. According to the World
Health Organization, the world's diabetic population has risen from 30 million in 1985, to 220 …

Diabetes mellitus (DM) is the leading cause of chronic kidney disease (CKD). Optimal
glycemic control contributes to improved outcomes in patients with DM, particularly for …

A recent International Expert Committee, jointly appointed by the American Diabetes
Association, the European Association for the Study of Diabetes, and the International …