Metabolic effects of ketogenic diets: exploring whole-body metabolism in connection with adipose tissue and other metabolic organs

Y Ahmad, DS Seo, Y Jang - International Journal of Molecular Sciences, 2024 - mdpi.com
The ketogenic diet (KD) is characterized by minimal carbohydrate, moderate protein, and
high fat intake, leading to ketosis. It is recognized for its efficiency in weight loss, metabolic …

Regulation of adipocyte thermogenesis: mechanisms controlling obesity

MF Hussain, A Roesler, L Kazak - The FEBS journal, 2020 - Wiley Online Library
Adipocyte biology has been intensely researched in recent years due to the emergence of
obesity as a serious global health concern and because of the realization that adipose …

Sirt3 ameliorates mitochondrial dysfunction and oxidative stress through regulating mitochondrial biogenesis and dynamics in cardiomyoblast.

P Bugga, MJ Alam, R Kumar, S Pal, N Chattopadyay… - Cellular …, 2022 - Elsevier
Sirtuins are the endogenously present anti-aging protein deacetylases that regulate the
mitochondrial biogenesis and function. Especially Sirt3, a mitochondrial sirtuin, is well …

Sirtuin 3 deficiency exacerbates diabetic cardiomyopathy via necroptosis enhancement and NLRP3 activation

S Song, Y Ding, G Dai, Y Zhang, M Xu, J Shen… - Acta Pharmacologica …, 2021 - nature.com
Abstract Sirtuin 3 (SIRT3) is a potential therapeutic target for cardiovascular, metabolic, and
other aging-related diseases. In this study, we investigated the role of SIRT3 in diabetic …

Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1

H Cheng, R Sebaa, N Malholtra, B Lacoste… - Nature …, 2021 - nature.com
Naked mole-rats are among the most hypoxia-tolerant mammals. During hypoxia, their body
temperature (T b) decreases via unknown mechanisms to conserve energy. In small …

Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation

J Park, HL Kim, Y Jung, KS Ahn, HJ Kwak, JY Um - Nutrients, 2019 - mdpi.com
Obesity is a global health threat. Herein, we evaluated the underlying mechanism of anti-
obese features of bitter orange (Citrus aurantium Linné, CA). Eight-week-administration of …

[HTML][HTML] Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans

UD Mueez, VD de Mello, M Tuomainen, J Raiko… - Cell Reports, 2023 - cell.com
Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic
health. In murine BAT, cold increases the fundamental molecule for mitochondrial function …

CircRNA-mediated regulation of brown adipose tissue adipogenesis

K Liu, X Liu, Y Deng, Z Li, A Tang - Frontiers in Nutrition, 2022 - frontiersin.org
Adipose tissue represents a candidate target for the treatment of metabolic illnesses, such
as obesity. Brown adipose tissue (BAT), an important heat source within the body, promotes …

Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues

A Ayari, M Rosa-Calatrava, S Lancel… - Communications …, 2020 - nature.com
Like all obligate intracellular pathogens, influenza A virus (IAV) reprograms host cell's
glucose and lipid metabolism to promote its own replication. However, the impact of …

[HTML][HTML] Sirtuins-mediated system-level regulation of mammalian tissues at the interface between metabolism and cell cycle: a systematic review

P Maissan, EJ Mooij, M Barberis - Biology, 2021 - mdpi.com
Biology | Free Full-Text | Sirtuins-Mediated System-Level Regulation of Mammalian Tissues at
the Interface between Metabolism and Cell Cycle: A Systematic Review Next Article in Journal …