Post-stroke depression: mechanisms and pharmacological treatment
Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …
affects survivals' functional outcome, response to rehabilitation and quality of life …
[HTML][HTML] Behavioral tests in rodent models of stroke
J Ruan, Y Yao - Brain hemorrhages, 2020 - Elsevier
Rodents are the most widely used experimental animals in stroke research due to their
similar vascular anatomy, high reproductive rates, and availability of transgenic models …
similar vascular anatomy, high reproductive rates, and availability of transgenic models …
Behavioral outcome measures to improve experimental stroke research
Functional recovery after an experimental stroke can be assessed by multiple behavioral
tests, however, there is no consensus about which test to use in long-term stroke recovery …
tests, however, there is no consensus about which test to use in long-term stroke recovery …
Mechanisms and therapeutic targets of depression after intracerebral hemorrhage
Y Wu, L Wang, K Hu, C Yu, Y Zhu, S Zhang… - Frontiers in …, 2018 - frontiersin.org
The relationship between depression and intracerebral hemorrhage (ICH) is complicated.
One of the most common neuropsychiatric comorbidities of hemorrhagic stroke is Post-ICH …
One of the most common neuropsychiatric comorbidities of hemorrhagic stroke is Post-ICH …
Optimizing functional outcome endpoints for stroke recovery studies
Novel therapeutic intervention that aims to enhance the endogenous recovery potential of
the brain during the subacute phase of stroke has produced promising results. The …
the brain during the subacute phase of stroke has produced promising results. The …
Depression of pyroptosis by inhibiting caspase-1 activation improves neurological outcomes of kernicterus model rats
S Li, H Huang, Q Wei, C He, J Feng… - ACS Chemical …, 2021 - ACS Publications
Kernicterus is a severe complication of extreme neonatal hyperbilirubinemia. Prolonged
exposure to high-level unconjugated bilirubin (UCB) directly damages brain tissue …
exposure to high-level unconjugated bilirubin (UCB) directly damages brain tissue …
Combined use of spatial restraint stress and middle cerebral artery occlusion is a novel model of post-stroke depression in mice
G Zhang, L Chen, L Yang, X Hua, B Zhou, Z Miao… - Scientific reports, 2015 - nature.com
Post stroke depression (PSD) is one of the most common complications of ischemic stroke.
At present, the underlying mechanisms are unclear, largely because there are no reliable …
At present, the underlying mechanisms are unclear, largely because there are no reliable …
Indoleamine 2, 3‐dioxygenase‐dependent neurotoxic kynurenine metabolism contributes to poststroke depression induced in mice by ischemic stroke along with …
YS Koo, H Kim, JH Park, MJ Kim, YI Shin… - Oxidative Medicine …, 2018 - Wiley Online Library
Aim. Poststroke depression (PSD), which occurs in approximately one‐third of stroke
survivors, is clinically important because of its association with slow functional recovery and …
survivors, is clinically important because of its association with slow functional recovery and …
Buyang huanwu decoction ameliorates poststroke depression via promoting neurotrophic pathway mediated neuroprotection and neurogenesis
L Luo, S Deng, J Yi, S Zhou, Y She… - … and Alternative Medicine, 2017 - Wiley Online Library
Objective. The aim of the present research is to investigate the therapeutic effect of Buyang
Huanwu Decoction (BHD) in poststroke depression (PSD) animal model and illustrate its …
Huanwu Decoction (BHD) in poststroke depression (PSD) animal model and illustrate its …
Anti-depressant effects of phosphodiesterase 3 inhibitor cilostazol in chronic mild stress-treated mice after ischemic stroke
YR Kim, HN Kim, KW Hong, HK Shin, BT Choi - Psychopharmacology, 2016 - Springer
Abstract Rationale Phosphodiesterase 3 (PDE3) inhibitor cilostazol ameliorates negative
effects of cerebral hypoperfusion against cerebral ischemic injury through the …
effects of cerebral hypoperfusion against cerebral ischemic injury through the …