[HTML][HTML] Engineered hydrogels for peripheral nerve repair

Y Liu, X Zhang, C Xiao, B Liu - Materials Today Bio, 2023 - Elsevier
Peripheral nerve injury (PNI) is a complex disease that often appears in young adults. It is
characterized by a high incidence, limited treatment options, and poor clinical outcomes …

Prospects of using chitosan-based biopolymers in the treatment of peripheral nerve injuries

M Zhang, H An, F Zhang, H Jiang, T Wan… - International Journal of …, 2023 - mdpi.com
Peripheral nerve injuries are common neurological disorders, and the available treatment
options, such as conservative management and surgical repair, often yield limited results …

Chitosan nerve conduit filled with ZIF-8-functionalized guide microfibres enhances nerve regeneration and sensory function recovery in sciatic nerve defects

X Zhang, T Qi, Y Sun, X Chen, P Yang, S Wei… - Chemical Engineering …, 2024 - Elsevier
Nerve conduits have shown promise as alternatives to autologous nerves, but their repair
effects need to be improved. The topographical guidance and functionalization of scaffolds …

[HTML][HTML] Natural polysaccharides and their derivatives as potential medical materials and drug delivery systems for the treatment of peripheral nerve injuries

SO Solomevich, CM Oranges, DF Kalbermatten… - Carbohydrate …, 2023 - Elsevier
Peripheral nerve repair following injury is one of the most serious problems in neurosurgery.
Clinical outcomes are often unsatisfactory and associated with a huge socioeconomic …

Hydrogels for neural regeneration: exploring new horizons

H Omidian, SD Chowdhury, LX Cubeddu - Materials, 2024 - pmc.ncbi.nlm.nih.gov
Nerve injury can significantly impair motor, sensory, and autonomic functions.
Understanding nerve degeneration, particularly Wallerian degeneration, and the …

Adhesive chitosan-based hybrid biohydrogels for peripheral nerve injury repair

P Qiu, L Wang, J Wang, X Wang, J Xu, X An… - Frontiers in Cell and …, 2024 - frontiersin.org
With the rapid progress of industrialization, the incidence of peripheral nerve injuries caused
by trauma has been continuously increasing. These injuries result in a significant number of …

Energy‐Dissipative Hydrogels: A Promising Material for Tissue Regeneration

M Li, Y Lin, Y Zhang, L Bian… - Chinese Journal of …, 2023 - Wiley Online Library
Comprehensive Summary Hydrogels are promising candidates for mimicking native
extracellular matrix (ECM) and are therefore widely adopted as scaffolds in tissue …

Sustainable Release Selenium Laden with SiO2 Restoring Peripheral Nerve Injury via Modulating PI3K/AKT Pathway Signaling Pathway

J Song, H Meng, G Deng, H Lin - International Journal of …, 2024 - Taylor & Francis
Background Inhibiting ROS overproduction is considered a very effective strategy for the
treatment of peripheral nerve injuries, and Se has a remarkable antioxidant effect; however …

Biomimetic-inspired piezoelectric ovalbumin/BaTiO3 scaffolds synergizing with anisotropic topology for modulating Schwann cell and DRG behavior

H Gao, Y Liu, H Shen, W Guan, S Sun, T Zheng… - International Journal of …, 2024 - Elsevier
The treatment of peripheral nerve injury is a clinical challenge that tremendously affected the
patients' health and life. Anisotropic topographies and electric cues can simulate the …

Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration

R Han, L Luo, C Wei, Y Qiao, J Xie… - Neural Regeneration …, 2025 - journals.lww.com
Neuronal growth, extension, branching, and formation of neural networks are markedly
influenced by the extracellular matrix—a complex network composed of proteins and …