Next-generation interfaces for studying neural function

JA Frank, MJ Antonini, P Anikeeva - Nature biotechnology, 2019 - nature.com
Monitoring and modulating the diversity of signals used by neurons and glia in a closed-loop
fashion is necessary to establish causative links between biochemical processes within the …

Brain energy metabolism: A roadmap for future research

CD Rae, JA Baur, K Borges, G Dienel… - Journal of …, 2024 - Wiley Online Library
Although we have learned much about how the brain fuels its functions over the last
decades, there remains much still to discover in an organ that is so complex. This article lays …

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

CA Tagge, AM Fisher, OV Minaeva… - Brain, 2018 - academic.oup.com
The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …

Fiber-based electrochemical biosensors for monitoring pH and transient neurometabolic lactate

MA Booth, SAN Gowers, M Hersey, IC Samper… - Analytical …, 2021 - ACS Publications
Developing tools that are able to monitor transient neurochemical dynamics is important to
decipher brain chemistry and function. Multifunctional polymer-based fibers have been …

Selective colorimetric urine glucose detection by paper sensor functionalized with polyaniline nanoparticles and cell membrane

T Lee, I Kim, S Roh, HG Jung, SW Lee, HS Kim… - Analytica Chimica …, 2021 - Elsevier
For the diabetes diagnosis, noninvasive methods are preferred to invasive methods; urine
glucose measurement is an example of a noninvasive method. However, conventional …

Measurement of Electrophysiological Signals In Vitro Using High‐Performance Organic Electrochemical Transistors

JE Tyrrell, MG Boutelle… - Advanced Functional …, 2021 - Wiley Online Library
Biological environments use ions in charge transport for information transmission. The
properties of mixed electronic and ionic conductivity in organic materials make them ideal …

Recent advances in in vivo neurochemical monitoring

C Tan, EM Robbins, B Wu, XT Cui - Micromachines, 2021 - mdpi.com
The brain is a complex network that accounts for only 5% of human mass but consumes
20% of our energy. Uncovering the mysteries of the brain's functions in motion, memory …

3D Printed Customizable Microsampling Devices for Neuroscience Applications

PM Pysz, JK Hoskins, M Zou… - ACS Chemical …, 2023 - ACS Publications
Multifunctional devices that incorporate chemical or physical measurements combined with
ways to manipulate brain tissue via drug delivery, electrical stimulation, or light for …

A Fiber Sensor for Long‐Term Monitoring of Extracellular Potassium Ion Fluctuations in Chronic Neuropsychiatric Diseases

J Wang, L Wang, Y Yang, HJ Li, X Huang… - Advanced …, 2024 - Wiley Online Library
The extracellular potassium ion concentration in the brain exerts a significant influence on
cellular excitability and intercellular communication. Perturbations in the extracellular …

3D printed microfluidic device for online detection of neurochemical changes with high temporal resolution in human brain microdialysate

IC Samper, SAN Gowers, ML Rogers, DSRK Murray… - Lab on a Chip, 2019 - pubs.rsc.org
This paper presents the design, optimisation and fabrication of a mechanically robust 3D
printed microfluidic device for the high time resolution online analysis of biomarkers in a …