This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Adipose tissue secretes bioactive peptides, termed 'adipokines', which act locally and
distally through autocrine, paracrine and endocrine effects. In obesity, increased production …

Resistin is a cysteine-rich protein postulated to be a molecular link between obesity and type
2 diabetes. The aim of this study was to investigate the role of PPARγ in the regulation of …

The discovery of resistin 10 years ago as a fat cell-secreted factor that modulates insulin
resistance suggested a link to the current obesity-associated epidemics of diabetes and …

Resistin is a novel adipocyte-secreted hormone proposed to link obesity with diabetes.
Studies in mice have revealed conflicting data however, and the physiological role of …

Obesity and noninsulin‐dependent diabetes mellitus are globally epidemic. Insulin
resistance is a major contributor to the pathogenesis of type II diabetes and plays a role in …

Resistin is a member of a class of cysteine-rich proteins collectively termed resistin-like
molecules. Resistin has been implicated in the pathogenesis of obesity-mediated insulin …

Diabetic foot ulcerations have been extensively reported as vascular complications of
diabetes mellitus associated with a high degree of morbidity and mortality. Diabetic foot …

This is the tenth update of the human obesity gene map, incorporating published results up
to the end of October 2003 and continuing the previous format. Evidence from single‐gene …

Diabetic foot ulcerations have been extensively reported as vascular complications of
diabetes mellitus associated with a high degree of morbidity and mortality; in fact, some …