Esophageal cancer (EC) is one of the most lethal cancers in the world, and its morbidity and
mortality rates rank among the top ten in China. Currently, surgical resection, radiotherapy …

Complex multicellular organisms have evolved sophisticated mechanisms to rapidly resolve
epithelial injuries. Epithelial integrity is critical to maintaining internal homeostasis. An …

Background Patients with human epidermal growth factor receptor 2-positive (HER2-
positive) cancers have a high incidence of central nervous system (CNS) spread, but …

Esophageal cancer is the eighth most common cancer and the sixth leading cause of cancer-
related death worldwide. Surgery is the primary form of treatment, but the survival is poor …

Various gram-negative pathogens express type IV secretion systems (T4SSs) which
translocate bacterial virulence factors into host target cells to hijack cellular processes for …

In recent years, a growing number of clinical studies have shown that immune checkpoint
inhibitor (ICI) can increase the remission rate and improve the prognosis of patients with …

Abstract CMTM3 (CKLF-like MARVEL transmembrane domain containing 3), a tumor
suppressor gene, is involved in multiple types of malignancies. CMTM3 knockdown …

Diarrhoea is a common, debilitating and potentially life threatening toxicity of many cancer
therapies. While the mechanisms of diarrhoea induced by traditional chemotherapy have …

Background We performed a systematic review and meta-analysis of the correlation
between cetuximab-induced skin rash and outcomes of solid tumor patients treated with …

Purpose The purpose of this study was to investigate the potential effect of activation of
epidermal growth factor receptor (EGFR) signaling pathway on the expression of …