Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

KR Gajbhiye, R Salve, M Narwade, A Sheikh… - Molecular Cancer, 2023 - Springer
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery

M Narwade, A Shaikh, KR Gajbhiye, P Kesharwani… - Biomaterials …, 2023 - Springer
The non-specificity of standard anticancer therapies has profound detrimental
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …

Engineered mesoporous silica nanoparticles, new insight nanoplatforms into effective cancer gene therapy

R Heidari, V Assadollahi, P Khosravian… - International Journal of …, 2023 - Elsevier
The use of nucleic acid to control the expression of genes relevant to tumor progression is a
key therapeutic approach in cancer research. Therapeutics based on nucleic acid provide …

Biomarkers in Ovarian Cancer: Towards Personalized Medicine

C López-Portugués, M Montes-Bayón, P Díez - Proteomes, 2024 - mdpi.com
Ovarian cancer is one of the deadliest cancers in women. The lack of specific symptoms,
especially at the initial stages of disease development, together with the malignancy …

Recent advances in nanotechnology-based drug delivery systems for the diagnosis and treatment of reproductive disorders

B Acharya, A Behera, S Behera… - ACS Applied Bio …, 2024 - ACS Publications
Over the past decade, nanotechnology has seen extensive integration into biomedical
applications, playing a crucial role in biodetection, drug delivery, and diagnostic imaging …

TfR Aptamer-functionalized MSNs for enhancing targeted cellular uptake and therapy of cancer cells

J Zhang, J Shang, X Tang, X Xu - ACS omega, 2023 - ACS Publications
Mesoporous silica nanoparticles (MSNs), as novel nanocarriers for drug delivery in cancer
treatment, have attracted widespread concern because of their rich pore structure, large …

Cutting-edge advancements in anticancer drug delivery and scope for theranostics using biocompatible multifunctional mesoporous silica nanoparticles

S Sarnaik, D Bhatane, SR Pamshong… - Journal of Drug Delivery …, 2024 - Elsevier
With the advancement in nanotechnology, treatment of cancer has improved significantly in
the past few decades. However, the hunt for exciting new generation of nanocarriers has no …

Fabrication of etoposide-loaded folic-acid-clocked mesoporous nanoparticles: Investigation of lung cancer proliferation and induction of apoptosis and ferroptosis

W Chen, X Cao, S Wu, Y Huang - Process Biochemistry, 2024 - Elsevier
Etoposide (EPT) offers significant benefits in the tumor therapy domain. EPT may cause
ferroptosis in lung cancer cells; however, its limited bioavailability and low water solubility …

Aptamers Versus Vascular Endothelial Growth Factor (VEGF): A New Battle against Ovarian Cancer

Y Mishra, A Chattaraj, V Mishra, A Ranjan… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the diseases that causes a high mortality as it involves unregulated and
abnormal cell growth proliferation that can manifest in any body region. One of the typical …

An Insight into Mesoporous Silica Nanoparticles: Ray of Hope for Cancer Management

C Singh Chauhan, A Garg… - Current Cancer Therapy …, 2024 - ingentaconnect.com
Cancer is one of the fatal diseases leading to a high mortality rate. The conventional
formulations available for the treatment of cancer are associated with several drawbacks …