[PDF][PDF] Manganese metabolism in humans

P Chen, J Bornhorst, MA Aschner - 2018 - publishup.uni-potsdam.de
Manganese (Mn) is an essential nutrient for intracellular activities; it functions as a cofactor
for a variety of enzymes, including arginase, glutamine synthetase (GS), pyruvate …

[HTML][HTML] Brain manganese and the balance between essential roles and neurotoxicity

RC Balachandran, S Mukhopadhyay, D McBride… - Journal of Biological …, 2020 - ASBMB
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

Mechanism and health effects of heavy metal toxicity in humans

GA Engwa, PU Ferdinand, FN Nwalo… - Poisoning in the …, 2019 - books.google.com
Several heavy metals are found naturally in the earth crust and are exploited for various
industrial and economic purposes. Among these heavy metals, a few have direct or indirect …

Heavy metals exposure and Alzheimer's disease and related dementias

KM Bakulski, YA Seo, RC Hickman… - Journal of …, 2020 - content.iospress.com
Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …

[HTML][HTML] Manganese toxicity upon overexposure: a decade in review

SL O'Neal, W Zheng - Current environmental health reports, 2015 - Springer
Exposure to manganese (Mn) causes clinical signs and symptoms resembling, but not
identical to, Parkinson's disease. Since our last review on this subject in 2004, the past …

Exposure to potentially toxic elements through ingestion of canned non-alcoholic drinks sold in Istanbul, Türkiye: a health risk assessment study

B Yüksel, F Ustaoğlu, MM Yazman, ME Şeker… - Journal of Food …, 2023 - Elsevier
High amounts of potentially toxic elements (PTEs) in non-alcoholic beverages can result in
acute or long-term intoxication. Trace amounts of PTEs like arsenic, cadmium, lead, mercury …

[HTML][HTML] Association between heavy metal exposure and Parkinson's disease: a review of the mechanisms related to oxidative stress

S Pyatha, H Kim, D Lee, K Kim - Antioxidants, 2022 - mdpi.com
Parkinson's disease (PD) is a gradually progressing neurodegenerative condition that is
marked by a loss of motor coordination along with non-motor features. Although the precise …

[HTML][HTML] Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity

KS Kirkley, KA Popichak, MF Afzali, ME Legare… - Journal of …, 2017 - Springer
Background As the primary immune response cell in the central nervous system, microglia
constantly monitor the microenvironment and respond rapidly to stress, infection, and injury …

Metals associated neurodegeneration in Parkinson's disease: Insight to physiological, pathological mechanisms and management

K Raj, P Kaur, GD Gupta, S Singh - Neuroscience Letters, 2021 - Elsevier
Parkinson's disease (PD) is a deliberately progressive neurological disorder, arises due to
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The …

[图书][B] Trace elements in abiotic and biotic environments

A Kabata-Pendias, B Szteke - 2015 - library.oapen.org
This book helps readers understand the fundamental principles and phenomena that control
the transfer of trace elements. It describes the occurrence and behavior of trace elements in …