Pathogenesis and virulence of Candida albicans
JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
TH17 cell heterogeneity and its role in tissue inflammation
Since their discovery almost two decades ago, interleukin-17-producing CD4+ T cells (TH17
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …
[HTML][HTML] Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination
SARS-CoV-2 mRNA vaccines have shown remarkable clinical efficacy, but questions
remain about the nature and kinetics of T cell priming. We performed longitudinal antigen …
remain about the nature and kinetics of T cell priming. We performed longitudinal antigen …
Role of the IL-23/IL-17 pathway in rheumatic diseases: an overview
C Schinocca, C Rizzo, S Fasano, G Grasso… - Frontiers in …, 2021 - frontiersin.org
Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19)
and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12). IL-23 is mainly produced …
and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12). IL-23 is mainly produced …
CD4 T helper cell subsets and related human immunological disorders
The immune system plays a critical role in protecting hosts from the invasion of organisms.
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …
The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives
C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
Intricacies of TGF-β signaling in Treg and Th17 cell biology
Balanced immunity is pivotal for health and homeostasis. CD4+ helper T (Th) cells are
central to the balance between immune tolerance and immune rejection. Th cells adopt …
central to the balance between immune tolerance and immune rejection. Th cells adopt …
Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy
A Basu, G Ramamoorthi, G Albert, C Gallen… - Frontiers in …, 2021 - frontiersin.org
Current success of immunotherapy in cancer has drawn attention to the subsets of TH cells
in the tumor which are critical for activation of anti-tumor response either directly by …
in the tumor which are critical for activation of anti-tumor response either directly by …
IL-17 receptor–based signaling and implications for disease
IL-17 is a highly versatile pro-inflammatory cytokine crucial for a variety of processes,
including host defense, tissue repair, the pathogenesis of inflammatory disease and the …
including host defense, tissue repair, the pathogenesis of inflammatory disease and the …
[HTML][HTML] Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals
Vaccine-mediated immunity often relies on the generation of protective antibodies and
memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth …
memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth …