Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin

CY Wong, H Al-Salami, CR Dass - International journal of pharmaceutics, 2018 - Elsevier
Diabetes mellitus is a chronic metabolic health disease affecting the homeostasis of blood
sugar levels. However, subcutaneous injection of insulin can lead to patient non …

Acrylate and methacrylate polymers' applications: Second life with inexpensive and sustainable recycling approaches

C Corsaro, G Neri, A Santoro, E Fazio - Materials, 2021 - mdpi.com
Polymers are widely employed in several fields thanks to their wide versatility and the easy
derivatization routes. However, a wide range of commercial polymers suffer from limited use …

Enhanced oral delivery of insulin via the colon-targeted nanocomposite system of organoclay/glycol chitosan/Eudragit®S100

SH Lee, SY Back, JG Song, HK Han - Journal of Nanobiotechnology, 2020 - Springer
This study aimed to develop a ternary nanocomposite system of organoclay, glycol-chitosan,
and Eudragit® S100 as an effective colon targeted drug delivery carrier to enhance the oral …

Mesalamine-loaded alginate microspheres filled in enteric coated HPMC capsules for local treatment of ulcerative colitis: in vitro and in vivo characterization

VC Patole, AP Pandit - Journal of Pharmaceutical Investigation, 2018 - Springer
An attempt was made to formulate mesalamine-loaded alginate microspheres by emulsion
cross linking method for local treatment of ulcerative colitis. Microspheres were filled in …

pH-sensitive poly (lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin

S Sun, N Liang, H Yamamoto… - International journal …, 2015 - Taylor & Francis
This study proposes a new concept of pH-sensitive poly (lactide-co-glycolide)(PLGA)
nanoparticle composite microcapsules for oral delivery of insulin. Firstly, insulin–sodium …

A quality by design (QbD) study on enoxaparin sodium loaded polymeric microspheres for colon-specific delivery

D Hales, L Vlase, SA Porav, A Bodoki… - European Journal of …, 2017 - Elsevier
The aim of this study was to apply quality by design (QbD) for pharmaceutical development
of enoxaparin sodium microspheres for colon-specific delivery. The Process Parameters …

Stimuli-responsive polysaccharides for colon-targeted drug delivery

A Tiwari, A Verma, PK Panda, S Saraf, A Jain… - … nanocarriers for drug …, 2019 - Elsevier
Polysaccharides are widely available, inexpensive and versatile polymer having good
stability, safety, low biotoxicity, hydrophilicity, gelling ability, flexibility for chemical …

Eudragit® FS Microparticles Containing Bacteriophages, Prepared by Spray-Drying for Oral Administration

E Tabare, T Dauchot, C Cochez, T Glonti, C Antoine… - Pharmaceutics, 2023 - mdpi.com
Phage therapy is recognized to be a promising alternative to fight antibiotic-resistant
infections. In the quest for oral dosage forms containing bacteriophages, the utilization of …

Drug loading strategy of modular self‐assembly mode: Curcumin pyrimidine derivatives mediated by pH‐sensitive materials

J Feng, S Wang, Y Liu, M Zhou, T Chai… - Journal of Polymer …, 2024 - Wiley Online Library
Chemotherapy drugs often cause various adverse reactions and affect normal tissues, so it
is of great significance to design effective targeted anti‐tumor drug delivery methods. We …