Advances in the field of boron chemistry have expanded the application of this element in
Medicinal Chemistry. Boron-containing compounds represent a new class for medicinal …

Aminoacyl-tRNA synthetases (ARSs) are essential enzymes for protein synthesis with
evolutionarily conserved enzymatic mechanisms. Despite their similarity across organisms …

The currently available anti-Toxoplasma agents have serious limitations. This systematic
review was performed to evaluate drugs and new compounds used for the treatment of …

Aminoacyl-tRNA synthetases (ARSs) are universal enzymes that catalyze the attachment of
amino acids to the 3′ ends of their cognate tRNAs. The resulting aminoacylated tRNAs are …

Aminoacyl-tRNA synthetases (ARSs) play a vital role in protein synthesis by linking amino
acids to their cognate transfer RNAs (tRNAs). This typical function has been well recognized …

Benzoxaboroles are effective against bacterial, fungal and protozoan pathogens. We report
potent activity of the benzoxaborole AN3661 against Plasmodium falciparum laboratory …

Toxoplasmosis is an infection caused by Toxoplasma gondii, a widespread zoonotic
protozoan which poses a great threat to human health and economic well-being worldwide …

Parasitic diseases result in considerable human morbidity and mortality. The continuous
emergence and spread of new drug-resistant parasite strains is an obstacle to controlling …

Introduction Cryptosporidiosis is a leading cause of diarrheal-associated morbidity and
mortality, predominantly affecting children under 5 years old in low-and-middle-income …

Cryptosporidium is a protozoan parasite and a leading cause of diarrheal disease and
mortality in young children. Currently, there are no fully effective treatments available to cure …