The indole scaffold is one of the most widespread heterocycles in the naturally occurring
and synthetic bioactive compounds including anticancer agents. Due to its biodiversity and …

The growing incidence of microorganisms that resist antimicrobials is a constant concern for
the scientific community, while the development of new antimicrobials from new chemical …

Abstract Wild Syrian rue (Peganum harmala L. family Zygophyllaceae) is well-known in Iran
and various parts of this plant including, its seeds, bark, and root have been used as folk …

β-Carboline alkaloids are a large group of natural and synthetic indole alkaloids with
different degrees of aromaticity, some of which are widely distributed in nature, including …

Abstract β-Carbolines are indole alkaloids having a tricyclic pyrido [3, 4-b] indole ring in their
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …

Peganum harmala L. is a multipurpose medicinal plant increasingly used for psychoactive
recreational purposes (Ayahuasca analog). Harmaline, harmine, harmalol, harmol and …

Peganum harmala L. is known as Syrian rue, Wild rue and Harmal. P. harmala extracts are
considered important for drug development, because they are reported to have numerous …

Anticancer drugs are often nonselective antiproliferative agents (cytotoxins) that
preferentially kill dividing cells by attacking their DNA at some level. The lack of selectivity …

Ethnopharmacological relevance The plants of the genus Peganum have a long history as a
Chinese traditional medicine for the treatment of cough, hypertension, diabetes, asthma …

Ethnopharmacological relevance In the study area, knowledge related to the traditional uses
of medicinal plants is totally in the custody of elder community members and local herbalists …