A review of cancer genetics and genomics studies in Africa

SO Rotimi, OA Rotimi, B Salhia - Frontiers in oncology, 2021 - frontiersin.org
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

[PDF][PDF] Clinical significance of fibroblast growth factor receptor-3 mutations in bladder cancer: a systematic review and meta-analysis

X Liu, W Zhang, D Geng, J He, Y Zhao, L Yu - Genet Mol Res, 2014 - funpecrp.com.br
Mutations in the fibroblast growth factor receptor-3 (FGFR3) gene are frequently found in
bladder cancer, but their prognostic value remains controversial. To globally summarize the …

Smoking intensity and bladder cancer aggressiveness at diagnosis

ALA Barbosa, SHHM Vermeulen, KK Aben… - PLoS …, 2018 - journals.plos.org
Objective To explore the relation between cigarette smoking intensity and bladder cancer
aggressiveness at first diagnosis. Methods Patients diagnosed with urinary bladder cancer …

FGFR3 overexpression is prognostic of adverse outcome for muscle-invasive bladder carcinoma treated with adjuvant chemotherapy

JY Sung, JM Sun, BC Jeong, SI Seo, SS Jeon… - … Oncology: Seminars and …, 2014 - Elsevier
Background Alterations in fibroblast growth factor receptor 3 (FGFR3) have been implicated
in the pathogenesis of urothelial carcinoma. However, its clinicopathological significance …

A Meta-Analysis of the Relationship between FGFR3 and TP53 Mutations in Bladder Cancer

Y Neuzillet, X Paoletti, S Ouerhani, P Mongiat-Artus… - PloS one, 2012 - journals.plos.org
TP53 and FGFR3 mutations are the most common mutations in bladder cancers. FGFR3
mutations are most frequent in low-grade low-stage tumours, whereas TP53 mutations are …

The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

K Rouissi, IB Bahria, K Bougatef, R Marrakchi… - BMC cancer, 2011 - Springer
Background In this work, we have conducted a case-control study in order to assess the
effect of tobacco and three genetic polymorphisms in XPC, ERCC2 and ERCC5 genes …

The mutational spectrum of HRAS, KRAS, NRAS and FGFR3 genes in bladder cancer

S Ouerhani, ABA Elgaaied - Cancer Biomarkers, 2012 - content.iospress.com
Bladder cancer is one of the most common cancers worldwide. A number of genetic and
epigenetic alterations have been identified in bladder tumorigenesis, including activating …

Nitrated polycyclic aromatic hydrocarbon (nitro-PAH) signatures and somatic mutations in diesel exhaust-exposed bladder tumors

N Gonzalez, N Rao, M Dean, D Lee, AN Hurson… - … Biomarkers & Prevention, 2023 - AACR
Background: Diesel exhaust is a complex mixture, including polycyclic aromatic
hydrocarbons (PAH) and nitrated PAHs (nitro-PAH), many of which are potent mutagens and …

miR-143 expression profiles in urinary bladder cancer: correlation with clinical and epidemiological parameters

NS Boubaker, M Spagnuolo, N Trabelsi, R Said… - Molecular Biology …, 2020 - Springer
Abstract Hsa-mir-143 and hsa-let-7c have been reported to be deregulated in multiple
neoplasms. The main purpose of this study was to investigate the expression of these …

Cytoplasmic Androgen Receptor, CD24 Expression and Smoking Intensity to Urothelial Carcinoma of the Bladder Invasiveness: A Cross-Sectional Study

SV Pramod, F Safriadi, BS Hernowo… - … and Reports in …, 2023 - Taylor & Francis
Purpose To the best of our knowledge, Androgen receptor (AR) and cluster of differentiation
24 (CD24) expression in bladder urothelial carcinoma (UC) has not yet been reported in our …