Protein‐protein interaction plays key role in predicting the protein function of target protein
and drug ability of molecules. The majority of genes and proteins realize resulting …

During a decade of proof-of-principle analysis in model organisms, protein networks have
been used to further the study of molecular evolution, to gain insight into the robustness of …

As the scientific enterprise has grown in size and diversity, we need empirical evidence on
the research process to test and apply interventions that make it more efficient and its results …

Abstract Pathway Commons (http://www. pathwaycommons. org) is a collection of publicly
available pathway data from multiple organisms. Pathway Commons provides a web-based …

Networks and network analysis are arguably one of the largest growth areas of the early
twenty-first century in the quantitative sciences. Despite roots in social network analysis …

Current yeast interactome network maps contain several hundred molecular complexes with
limited and somewhat controversial representation of direct binary interactions. We carried …

After the completion of the human and other genome projects it emerged that the number of
genes in organisms as diverse as fruit flies, nematodes, and humans does not reflect our …

Mapping protein–protein interactions for chromatin-associated proteins remains
challenging. Here we explore the use of BioID, a proximity biotinylation approach in which a …

Motivation: Identification of functional modules in protein interaction networks is a first step in
understanding the organization and dynamics of cell functions. To ensure that the identified …

To elucidate cellular machinery on a global scale, we performed a multiple comparison of
the recently available protein–protein interaction networks of Caenorhabditis elegans …