Chemical and biological properties of the world's most expensive spice: Saffron

JP Melnyk, S Wang, MF Marcone - Food research international, 2010 - Elsevier
Saffron (Crocus sativus, L.) is traditionally used as a coloring or flavoring agent, but recent
research has shown its potential to promote health. The constituents of interest include …

Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.)

FI Abdullaev - Experimental biology and medicine, 2002 - journals.sagepub.com
Since cancer is the most common cause of death in the world population, the possibility that
readily available natural substances from plants, vegetables, herbs, and spices may be …

[HTML][HTML] Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice

H Hosseinzadeh, HM Younesi - BMC pharmacology, 2002 - Springer
Background Crocus sativus L.(saffron) is used in folk medicine, for example as an
antiedematogenic agent. We aimed to evaluate the antinociceptive and anti-inflammatory …

Evaluation of microwave-assisted extraction technology for separation of bioactive components of saffron (Crocus sativus L.)

M Sarfarazi, SM Jafari, G Rajabzadeh… - Industrial Crops and …, 2020 - Elsevier
Saffron is the most expensive spice in the world and it is necessary to develop efficient
extraction methods for separation of its bioactive compounds. The aim of this study was to …

Quantification of saffron (Crocus sativus L.) metabolites crocins, picrocrocin and safranal for quality determination of the spice grown under different environmental …

M Lage, CL Cantrell - Scientia horticulturae, 2009 - Elsevier
The primary goal of this study was to propose saffron as a sustainable substitute crop with
high added value in some Moroccan agricultural areas with low and erratic rainfalls, for their …

[HTML][HTML] The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review

S Nanda, K Madan - Heliyon, 2021 - cell.com
Reactive oxygen species (ROS) are produced as a result of various environmental factors
and cellular metabolism reactions creating oxidative stress. The reversible oxidative …

Biologically active compounds and pharmacological activities of species of the genus Crocus: A review

O Mykhailenko, V Kovalyov, O Goryacha, L Ivanauskas… - Phytochemistry, 2019 - Elsevier
The present article is the first comprehensive review on the chemical composition and
pharmacological activities of the raw materials of Crocus species. In the present review, data …

[HTML][HTML] Safranal: from an aromatic natural product to a rewarding pharmacological agent

R Rezaee, H Hosseinzadeh - Iranian journal of basic medical …, 2013 - ncbi.nlm.nih.gov
Safranal, the main component of Crocus sativus essential oil, is thought to be the main
cause of saffron unique odor. It is now about eighty years that this compound has been …

HPLC quantification of major active components from 11 different saffron (Crocus sativus L.) sources

H Caballero-Ortega, R Pereda-Miranda, FI Abdullaev - Food Chemistry, 2007 - Elsevier
Eleven certified saffron samples (Crocus sativus L.), one each from Azerbaijan, China,
Greece, France, India, Iran, Italy, New Zealand, Spain, Turkey and the Sigma Chemical …

Ameliorative effect of saffron aqueous extract on hyperglycemia, hyperlipidemia, and oxidative stress on diabetic encephalopathy in streptozotocin induced …

S Samarghandian, M Azimi-Nezhad… - BioMed research …, 2014 - Wiley Online Library
Diabetic encephalopathy is one of the severe complications in patients with diabetes
mellitus. Findings indicate that saffron extract has antioxidant properties but its underlying …