Background Guidelines from 2005 for treating suspected sepsis in low-and middle-income
countries (LMIC) recommended hospitalisation and prophylactic intramuscular (IM) or …

Neonatal infections are estimated to account for a quarter of the 2· 8 million annual neonatal
deaths, as well as approximately 3% of all disability-adjusted life-years. Despite this burden …

Background There is limited data on antibiotic treatment in hospitalized neonates in low-and
middle-income countries (LMICs). We aimed to describe patterns of antibiotic use …

Background Despite remarkable progress in the improvement of child survival between
1990 and 2015, the Millennium Development Goal (MDG) 4 target of a two-thirds reduction …

This is the eighteenth global report on tuberculosis (TB) published by WHO in a series that
started in 1997. It provides a comprehensive and up-to-date assessment of the TB epidemic …

Background Updated information on the cause of childhood mortality is essential for
developing policies and designing programmes targeting the major burden of disease …

Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of
drug substance, the necessary dose and the age-appropriateness of the formulation …

Background Severe infections remain one of the main causes of neonatal deaths worldwide.
Possible severe infection is diagnosed in young infants (aged 0–59 days) according to the …

Background Neonatal sepsis is a major cause of morbidity and mortality. It is the third
leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality …

Background Serious infections account for 25% of global newborn deaths annually, most in
low-resource settings where hospital-based treatment is not accessible or feasible. In …