Lizard tail regeneration as an instructive model of enhanced healing capabilities in an adult amniote
TP Lozito, RS Tuan - Connective tissue research, 2017 - Taylor & Francis
The ability to regenerate damaged or lost tissues has remained the lofty goal of regenerative
medicine. Unfortunately, humans, like most mammals, suffer from very minimal natural …
medicine. Unfortunately, humans, like most mammals, suffer from very minimal natural …
The anatomy and histology of caudal autotomy and regeneration in lizards
EAB Gilbert, SL Payne… - Physiological and …, 2013 - journals.uchicago.edu
Caudal autotomy—the ability to self-detach the tail—is a dramatic adaptation common to
many structural-grade lizards. For most species, tail loss is followed by the equally dramatic …
many structural-grade lizards. For most species, tail loss is followed by the equally dramatic …
Single-cell analysis of lizard blastema fibroblasts reveals phagocyte-dependent activation of Hedgehog-responsive chondrogenesis
AC Vonk, X Zhao, Z Pan, ML Hudnall… - Nature …, 2023 - nature.com
Lizards cannot naturally regenerate limbs but are the closest known relatives of mammals
capable of epimorphic tail regrowth. However, the mechanisms regulating lizard blastema …
capable of epimorphic tail regrowth. However, the mechanisms regulating lizard blastema …
Transcriptomic Analysis of Tail Regeneration in the Lizard Anolis carolinensis Reveals Activation of Conserved Vertebrate Developmental and Repair Mechanisms
Lizards, which are amniote vertebrates like humans, are able to lose and regenerate a
functional tail. Understanding the molecular basis of this process would advance …
functional tail. Understanding the molecular basis of this process would advance …
Histochemical, biochemical and cell biological aspects of tail regeneration in lizard, an amniote model for studies on tissue regeneration
L Alibardi - Progress in Histochemistry and Cytochemistry, 2014 - Elsevier
The present review summarizes biochemical, histochemical and immunocytochemical
aspects of the process of tissue regeneration in lizards, non-mammalian amniotes with high …
aspects of the process of tissue regeneration in lizards, non-mammalian amniotes with high …
Appendage regeneration in vertebrates: what makes this possible?
V Daponte, P Tylzanowski, A Forlino - Cells, 2021 - mdpi.com
The ability to regenerate amputated or injured tissues and organs is a fascinating property
shared by several invertebrates and, interestingly, some vertebrates. The mechanism of …
shared by several invertebrates and, interestingly, some vertebrates. The mechanism of …
Lizard tail skeletal regeneration combines aspects of fracture healing and blastema-based regeneration
TP Lozito, RS Tuan - Development, 2016 - journals.biologists.com
Lizards are amniotes with the remarkable ability to regenerate amputated tails. The early
regenerated lizard tail forms a blastema, and the regenerated skeleton consists of a …
regenerated lizard tail forms a blastema, and the regenerated skeleton consists of a …
Appendage regeneration in anamniotes utilizes genes active during larval‐metamorphic stages that have been lost or altered in amniotes: the case for studying lizard …
L Alibardi - Journal of morphology, 2020 - Wiley Online Library
This review elaborates the idea that organ regeneration derives from specific evolutionary
histories of vertebrates. Regenerative ability depends on genomic regulation of genes …
histories of vertebrates. Regenerative ability depends on genomic regulation of genes …
[HTML][HTML] Lizard tail regeneration: regulation of two distinct cartilage regions by Indian hedgehog
TP Lozito, RS Tuan - Developmental Biology, 2015 - Elsevier
Lizards capable of caudal autotomy exhibit the remarkable ability to “drop” and then
regenerate their tails. However, the regenerated lizard tail (RLT) is known as an “imperfect …
regenerate their tails. However, the regenerated lizard tail (RLT) is known as an “imperfect …
Deep-time evolution of regeneration and preaxial polarity in tetrapod limb development
NB Fröbisch, C Bickelmann, JC Olori, F Witzmann - Nature, 2015 - nature.com
Among extant tetrapods, salamanders are unique in showing a reversed preaxial polarity in
patterning of the skeletal elements of the limbs, and in displaying the highest capacity for …
patterning of the skeletal elements of the limbs, and in displaying the highest capacity for …