Highlights•Variation in both HLA and SARS-CoV-2 impact antigen presentation to T
cells.•HLA variation influences COVID-19 outcomes and T-cell responses to SARS-CoV …

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …

HLA is crucial for appropriate immune responses in several viral infections, as well as in
severe acute respiratory syndrome coronavirus‐2 (SARS CoV‐2). The unpredictable nature …

Background COVID-19 is a respiratory disease caused by a novel coronavirus called as
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Detected for the first …

SARS-CoV-2 appears to induce diverse innate and adaptive immune responses, resulting in
different clinical manifestations of COVID-19. Due to their function in presenting viral …

Objective To investigate the changes of Spike protein-HLA binding affinity profiles between
the Wuhan strain and two dominant variants, the Delta and the Omicron strains, among the …

Background The COVID‐19 pandemic has had a profound global impact, with variations in
susceptibility, severity, and mortality rates across different regions. While many factors can …

An important number of studies have been conducted on the potential association between
human leukocyte antigen (HLA) genes and COVID-19 susceptibility and severity since the …

In this study, we aimed to investigate whether specific HLA alleles found in patients from
Romania and the Republic of Moldova were associated with the severity of COVID-19 …

Background SARS-CoV-2 vaccines are effective at reducing symptomatic and asymptomatic
COVID-19. Limited studies have compared symptoms, threshold cycle (Ct) values from …