Emerging SERS biosensors for the analysis of cells and extracellular vesicles

MT Yaraki, A Tukova, Y Wang - Nanoscale, 2022 - pubs.rsc.org
Cells and their derived extracellular vesicles (EVs) or exosomes contain unique molecular
signatures that could be used as biomarkers for the detection of severe diseases such as …

Nanomaterial-based microfluidic systems for cancer biomarker detection: recent applications and future perspectives

Y Xiang, C Hu, G Wu, S Xu, Y Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Detecting cancer biomarkers (eg, circulating tumor cells, extracellular vehicles, nucleic
acids, and protein biomarkers) is vital for risk assessment and early diagnosis. Nanomaterial …

Roadmap for Plasmonic Nanoparticle sensors: current progress, challenges and Future prospects

K Kant, R Beeram, LG Cabaleiro, Y Cao… - Nanoscale …, 2024 - pubs.rsc.org
Plasmonic nanoparticles (NPs) have played a significant role in the evolution of modern
nanoscience and nanotechnology in terms of colloidal synthesis, general understanding of …

Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis

HS Tan, T Wang, HN Sun, A Liu, SS Li - TrAC Trends in Analytical …, 2023 - Elsevier
Cancer derived exosomal biomarkers (eg proteins, RNAs) could reflect important
information about the cancer microenvironment. For ultrasensitive analysis of exosomal …

Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers

S Surappa, P Multani, U Parlatan, PD Sinawang… - Lab on a Chip, 2023 - pubs.rsc.org
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …

Emerging integrated SERS-microfluidic devices for analysis of cancer-derived small extracellular vesicles

L Ngo, A Tukova, A Hassanzadeh-Barforoushi… - Lab on a Chip, 2023 - pubs.rsc.org
Cancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer
vesicles secreted from cancer cells to the extracellular environment. They carry distinct …

Si nanowire Bio-FET for electrical and label-free detection of cancer cell-derived exosomes

W Zhao, J Hu, J Liu, X Li, S Sun, X Luan… - Microsystems & …, 2022 - nature.com
Exosomes are highly important in clinical diagnosis due to their high homology with their
parental cells. However, conventional exosome detection methods still face the challenges …

Strong plasmon resonance coupling in micro-extraction SERS membrane for in situ detection of molecular aqueous solutions

C Li, B Man, C Zhang, J Yu, G Liu, M Tian, Z Li… - Sensors and Actuators B …, 2024 - Elsevier
In situ surface-enhanced Raman scattering (SERS) detection of trace analytes with high
sensitivity, especially in complex aqueous solution environments such as polluted water and …

Printed divisional optical biochip for multiplex visualizable exosome analysis at point‐of‐care

X Yang, Z Zhang, Y Wu, H Wang, Y Yun… - Advanced …, 2024 - Wiley Online Library
Rapid detection of various exosomes is of great significance in early diagnosis and
postoperative monitoring of cancers. Here, a divisional optical biochip is reported for …

High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses

J Li, R Guan, A Wuethrich, M Yan, J Cheng… - Analytical …, 2024 - ACS Publications
The molecular detection of multiple respiratory viruses provides evidence for the rational use
of drugs and effective health management. Herein, we developed and tested the clinical …