With the development of technology, more infants receive general anesthesia for surgery,
other interventions, or clinical examination at an early stage after birth. However, whether …

Sažetak Oxidative stress occurs when reactive oxygen species (ROS) production
overwhelms cell protection by antioxidants. This review is focused on general anaesthesia …

Sevoflurane (Sev) is one of the most widely used pediatric anesthetics. The major concern of
neonatal repeated application of Sev is its potential long‐term impairment of cognition and …

This study aimed to investigate the protective effects and underlying mechanisms of
cistanche on sevoflurane‐induced aged cognitive dysfunction rat model. Aged (24 months) …

Previous research has shown that exposure to volatile anesthetics can induce acute
neuroinflammation and neuroapoptopsis in neonatal rodents and that these events can lead …

Developmental neurotoxicity is a serious consequence of repeated exposure to sevoflurane
during the postnatal period. Neuroinflammation is closely related to sevoflurane-induced …

For decades, the neurotoxicity caused by anesthetics in mammalian brain development has
gained increasing attention. Exposure to anesthetics leads to neurotoxicity and apoptosis of …

Inhalation of hydrogen (H2) gas is therapeutically effective for cerebrovascular diseases,
neurodegenerative disorders, and neonatal brain disorders including pathologies induced …

Background. Isoflurane (ISO) has been extensively uses in general anesthesia and reported
to cause deoxyribonucleic acid (DNA) damage in prolonged surgical procedures …

Sevoflurane is one of the most commonly used general anesthetics for children and infants.
Recent research indicates that repeated exposure to sevoflurane in neonates induces …