Biomaterials play a fundamental role in disease management and the improvement of
health care. In recent years, there has been a significant growth in the diversity, function, and …

Bacteria have been thought to flee senescence by dividing into two identical daughter cells,
but this notion of immortality has changed over the last two decades. Asymmetry between …

Evidence of ageing in the bacterium Escherichia coli was a landmark finding in senescence
research, as it suggested that even organisms with morphologically symmetrical fission may …

Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently,
they have been linked to aging of Escherichia coli (E. coli) where protein aggregates …

Background How aging, being unfavourable for the individual, can evolve is one of the
fundamental problems of biology. Evidence for aging in unicellular organisms is far from …

Resource competition has driven the evolution of novel polyphenisms in numerous
organisms, enhancing fitness in constantly changing environmental conditions. In natural …

Evidence for ageing in symmetrically dividing bacteria such as Escherichia coli has
historically been conflicting. Early work found weak or no evidence. More recent studies …

Gene expression and growth rate are highly stochastic in Escherichia coli. Some of the
growth rate variations result from the deterministic and asymmetric partitioning of damage by …

The mutation rate is a fundamental factor in evolutionary genetics. Recently, mutation rates
were found to be strongly reduced at high density in a wide range of unicellular organisms …

In microbial ecology and physiology, growth rate and growth yield are among the most
fundamental parameters. The question whether the two are independent of each other or …