Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy
characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and …

ADAMTS proteins are a superfamily of 26 secreted molecules comprising two related, but
distinct families. ADAMTS proteases are zinc metalloendopeptidases, most of whose …

A 27-year-old patient with a history of severe obstetrical complications and arterial
thrombosis received a diagnosis of hereditary thrombotic thrombocytopenic purpura (TTP) …

Thrombotic microangiopathy (TMA), a pathological lesion observed in a wide spectrum of
diseases, is triggered by endothelial injury and/or dysfunction. Although TMA lesions are …

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal
thrombotic microangiopathy caused by autoantibody-mediated severe deficiency of …

Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra-rare
thrombomicroangiopathy caused by an inherited deficiency of a disintegrin and …

Background Congenital thrombotic thrombocytopenic purpura (TTP) results from severe
hereditary deficiency of ADAMTS13. The efficacy and safety of recombinant ADAMTS13 and …

Congenital thrombotic thrombocytopenic purpura is an autosomal recessive inherited
disease with a clinically heterogeneous course and an incompletely understood genotype …

A significant amount of clinical and research interest in thrombosis is focused on large
vessels (eg, stroke, myocardial infarction, deep venous thrombosis, etc.); however …

Hereditary Thrombotic Thrombocytopenic Purpura Hereditary thrombotic thrombocytopenic
purpura is an autosomal recessive disorder caused by the absence of a functional protease …