The use of natural antioxidants in cancer therapy has increased: first, due to the potential of
natural antioxidants to kill tumour cells and second, because of their capacity to protect …

Loss-of-function mutations in the human voltage-gated sodium channel NaV1. 7 result in a
congenital indifference to pain. Selective inhibitors of NaV1. 7 are therefore likely to be …

The health and life span of Drosophila melanogaster are partly determined by intestinal
barrier integrity, metabolic rate as well as stress response and the expression of longevity …

The present study evaluated the anti-inflammatory effects of 4-methylcyclopentadecanone (4-
MCPC) on edema models in mice and aimed to determine the safety of 4-MCPC after acute …

Campomanesia xanthocarpa (Myrtaceae) is used in Brazilian traditional medicine against
fever, diabetes, hypercholesteremic, obesity, and urinary diseases. In the present study, the …

This study assessed the anti-inflammatory effects of the essential oil from Piper vicosanum
leaves (OPV) and evaluated the toxicological potential of this oil through acute toxicity …

The present study was designed to search for compounds with analgesic activity from the
Schizophyllum commune (SC), which is widely consumed as edible and medicinal …

Jingzhaotoxin-34 (JZTX-34) is a selective inhibitor of tetrodotoxin-sensitive (TTX-S) sodium
channels. In this study, we found that JZTX-34 selectively acted on Nav1. 7 with little effect …

Lichens produce variety of secondary metabolites including depsides, depsidones and
dibenzofurans having multifunctional activity in response to external environmental …

Background: Inflammation is a response of the immune system, guarding the individual
against infection. It is a major burning problem worldwide and billions of individuals are …