Organs-on-a-chip (OOCs) are miniature tissues and organs grown in vitro that enable
modeling of human physiology and disease. The technology has emerged from converging …

Organ‐on‐chip models, developed using microengineering and microfluidic technologies,
aim to recreate physiological‐like microenvironments of organs or tissues as a tool to study …

Predictive testing of anticancer drugs remains a challenge. Bioengineered systems,
designed to mimic key aspects of the human tumor microenvironment, are now improving …

In the past decades, anticancer drug development brought the field of tumor engineering to
a new level by the need of robust test systems. Simulating tumor microenvironment in vitro …

Although rare among the general population, bone malignancies have a high rate of
incidence among children and adolescents and are associated with high mortality rates …

The lack of controllable in vitro models that can recapitulate the features of solid tumors such
as Ewing's sarcoma limits our understanding of the tumor initiation and progression and …

Studies of anticancer therapies in traditional cell culture models can demonstrate efficacy of
direct-acting compounds but lack the 3-dimensional arrangement of the tumor cells and their …

DIPARTIMENTO DI INGEGNERIA DELL’INFORMAZIONE CORSO DI LAUREA IN
INGEGNERIA BIOMEDICA “ANALISI DELLE ALTERNATIVE ALLA SPERIME Page 1 1 …