Virus infection and death receptor-mediated apoptosis
X Zhou, W Jiang, Z Liu, S Liu, X Liang - Viruses, 2017 - mdpi.com
Virus infection can trigger extrinsic apoptosis. Cell-surface death receptors of the tumor
necrosis factor family mediate this process. They either assist persistent viral infection or …
necrosis factor family mediate this process. They either assist persistent viral infection or …
Viruses and apoptosis
A Roulston, RC Marcellus… - Annual Reviews in …, 1999 - annualreviews.org
▪ Abstract Successful viral replication requires not only the efficient production and spread of
progeny, but also evasion of host defense mechanisms that limit replication by killing …
progeny, but also evasion of host defense mechanisms that limit replication by killing …
Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks
Y Pommier, O Sordet, S Antony, RL Hayward, KW Kohn - Oncogene, 2004 - nature.com
Intrinsic (innate) and acquired (adaptive) resistance to chemotherapy critically limits the
outcome of cancer treatments. For many years, it was assumed that the interaction of a drug …
outcome of cancer treatments. For many years, it was assumed that the interaction of a drug …
TNF-induced signaling in apoptosis
PC Rath, BB Aggarwal - Journal of clinical immunology, 1999 - Springer
Out of the almost 17 members of the TNF superfamily, TNF is probably the most potent
inducer of apoptosis. TNF activates both cell-survival and cell-death mechanisms …
inducer of apoptosis. TNF activates both cell-survival and cell-death mechanisms …
Viral hepatitis and liver cancer: the case of hepatitis C
M Levrero - Oncogene, 2006 - nature.com
Chronic infection with the hepatitis C virus (HCV) is a major risk factor for the development of
hepatocellular carcinoma (HCC) worldwide. The pathogenesis of HCC in HCV infection has …
hepatocellular carcinoma (HCC) worldwide. The pathogenesis of HCC in HCV infection has …
I. TNF-induced liver injury
CA Bradham, J Plümpe, MP Manns… - American Journal …, 1998 - journals.physiology.org
Tumor necrosis factor-α (TNF-α) functions as a two-edged sword in the liver. TNF-α is
required for normal hepatocyte proliferation during liver regeneration. It functions both as a …
required for normal hepatocyte proliferation during liver regeneration. It functions both as a …
Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties
KE Reed, CM Rice - The Hepatitis C Viruses, 2000 - Springer
Hepatitis C was first recognized as a distinct form of liver disease in the mid-1970s with the
advent of diagnostic tests for hepatitis A and B virus infection (A LTER et al. 1975; P RINCE …
advent of diagnostic tests for hepatitis A and B virus infection (A LTER et al. 1975; P RINCE …
Genetic mechanisms of hepatocarcinogenesis
MA Feitelson, B Sun, N Lale Satiroglu Tufan, J Liu… - Oncogene, 2002 - nature.com
The development of hepatocellular carcinoma (HCC) is a multistep process associated with
changes in host gene expression, some of which correlate with the appearance and …
changes in host gene expression, some of which correlate with the appearance and …
Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes
McLauchlan - Journal of viral hepatitis, 2000 - Wiley Online Library
The core protein of hepatitis C virus (HCV) is believed to form the capsid shell of virus
particles. Maturation of the protein is achieved through cleavage by host cell proteases to …
particles. Maturation of the protein is achieved through cleavage by host cell proteases to …
[PDF][PDF] Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence
A Cerny, FV Chisari - Hepatology, 1999 - Wiley Online Library
The immune response to viral antigens is thought to be responsible for viral clearance and
disease pathogenesis during hepatitis C virus (HCV) infection. In chronically infected …
disease pathogenesis during hepatitis C virus (HCV) infection. In chronically infected …