C-reactive protein as a biomarker for major depressive disorder?

L Orsolini, S Pompili, S Tempia Valenta, V Salvi… - International journal of …, 2022 - mdpi.com
The etiopathogenesis of depression is not entirely understood. Several studies have
investigated the role of inflammation in major depressive disorder. The present work aims to …

Neuroinflammation and oxidative stress in psychosis and psychosis risk

H Barron, S Hafizi, AC Andreazza… - International journal of …, 2017 - mdpi.com
Although our understanding of psychotic disorders has advanced substantially in the past
few decades, very little has changed in the standard of care for these illnesses since the …

Protein-C reactive as biomarker predictor of schizophrenia phases of illness? A systematic review

L Orsolini, F Sarchione, F Vellante… - Current …, 2018 - ingentaconnect.com
Background: Schizophrenia is a complex illness in which genetic, environmental, and
epigenetic components have been implicated. However, recently, psychiatric disorders …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Inhibition of glycogen synthase kinase 3 by lithium, a mechanism in search of specificity

D Chatterjee, JM Beaulieu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Inhibition of Glycogen synthase kinase 3 (GSK3) is a popular explanation for the effects of
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …

Mitochondrial dysfunction in schizophrenia

P Ni, S Chung - BioEssays, 2020 - Wiley Online Library
Schizophrenia (SCZ) is a severe neurodevelopmental disorder affecting 1% of populations
worldwide with a grave disability and socioeconomic burden. Current antipsychotic …

The complex interaction of mitochondrial genetics and mitochondrial pathways in psychiatric disease

AB Cuperfain, ZL Zhang, JL Kennedy… - Complex …, 2018 - karger.com
While accounting for only 2% of the body's weight, the brain utilizes up to 20% of the body's
total energy. Not surprisingly, metabolic dysfunction and energy supply-and-demand …

Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and …

A Kathuria, K Lopez-Lengowski, D McPhie… - Discover Mental …, 2023 - Springer
We compared transcriptomic profiles of cerebral organoids differentiated from induced
pluripotent stem cells of eight schizophrenia and eight bipolar disorder patients to identify …

Familial aggregation and shared genetic loading for major psychiatric disorders and type 2 diabetes

MH Su, YH Shih, YF Lin, PC Chen, CY Chen, PC Hsiao… - Diabetologia, 2022 - Springer
Aims/hypothesis Psychiatric disorders, such as schizophrenia (SCZ), major depressive
disorder (MDD) and bipolar disorder (BPD), are highly comorbid with type 2 diabetes …

Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells

S Michels, GK Ganjam, H Martins, GM Schratt… - Cell death …, 2018 - nature.com
Affective disorders such as major depression and bipolar disorder are among the most
prevalent forms of mental illness and their etiologies involve complex interactions between …