Identification of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive Genomics …

RS Naorem, BD Pangabam, SS Bora, G Goswami… - Molecules, 2022 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and
responsible for causing life-threatening infections. The emergence of hypervirulent and …

Identification of core therapeutic targets for Monkeypox virus and repurposing potential of drugs against them: An in silico approach

A Sahu, M Gaur, NC Mahanandia, E Subudhi… - Computers in Biology …, 2023 - Elsevier
Monkeypox virus (mpox virus) outbreak has rapidly spread to 82 non-endemic countries.
Although it primarily causes skin lesions, secondary complications and high mortality (1 …

Identification of a Novel Therapeutic Target against XDR Salmonella Typhi H58 Using Genomics Driven Approach Followed Up by Natural Products Virtual Screening

K Jalal, K Khan, M Hassam, MN Abbas, R Uddin… - Microorganisms, 2021 - mdpi.com
Typhoid fever is caused by a pathogenic, rod-shaped, flagellated, and Gram-negative
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …

An immunoinformatics-based designed multi-epitope candidate vaccine (mpme-VAC/STV-1) against Mycoplasma pneumoniae

TCV Rodrigues, AK Jaiswal, MR Lemes… - Computers in Biology …, 2022 - Elsevier
Pneumonia is a serious global health problem that accounts for over one million deaths
annually. Among the main microorganisms causing pneumonia, Mycoplasma pneumoniae …

Comparative genomics of Bordetella pertussis and prediction of new vaccines and drug targets

AG Felice, LNQ Santos, I Kolossowski… - Journal of …, 2022 - Taylor & Francis
Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis, a Gram-
negative bacterium described over a century ago. Despite broad vaccine coverage and …

[HTML][HTML] A Novel Surface-Exposed Polypeptide Is Successfully Employed as a Target for Developing a Prototype One-Step Immunochromatographic Strip for Specific …

SA Mohamed, TM Samir, OM Helmy, NM Elhosseiny… - Biomolecules, 2020 - mdpi.com
Neonatal sepsis is a life-threatening condition and Staphylococcus aureus is one of its major
causes. However, to date, no rapid and sensitive diagnostic tool has been developed for its …

New putative therapeutic targets against Serratia marcescens using reverse vaccinology and subtractive genomics

LCS Prado, A Giacchetto Felice… - Journal of …, 2022 - Taylor & Francis
Abstract The Gram-negative bacillus Serratia marcescens, a member of Enterobacteriaceae
family, is an opportunistic nosocomial pathogen commonly found in hospital outbreaks that …

[PDF][PDF] Identification of a novel therapeutic target against XDR Salmonella Typhi H58 using genomics driven approach followed up by natural products virtual …

K Jalal, K Khan, M Hassam, MN Abbas, R Uddin… - 2021 - academia.edu
Typhoid fever is caused by a pathogenic, rod-shaped, flagellated, and Gram-negative
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …

Pan-genomic analyses of 47 complete genomes of the Rickettsia genus and prediction of new vaccine targets and virulence factors of the species

AG Felice, LG Alves, ASF Freitas… - Journal of …, 2022 - Taylor & Francis
The genus Rickettsia belongs to the Proteobacteria phylum and these bacteria infect
animals and humans causing a range of diseases worldwide. The genus is divided into 4 …

Identification of Therapeutic drug Target of Stenotrophomonas maltophilia through subtractive genomic approach and in-silico screening based on 2D similarity …

R Chandela, D Jade, S Mohan… - … Chemistry & High …, 2022 - ingentaconnect.com
Background: Stenotrophomonas maltophilia is a multi-drug resistant, gram-negative
bacterium that causes opportunistic infections and is associated with high morbidity and …