A review of recent synthetic strategies and biological activities of isoxazole

CP Pandhurnekar, HC Pandhurnekar… - Journal of …, 2023 - Wiley Online Library
Among different heterocyclic compounds, isoxazole and their analogues are very important
classes of heterocyclic compounds as they display an extensive range of biological actions …

Nitro compounds as the core structures of promising energetic materials and versatile reagents for organic synthesis

SG Zlotin, IL Dalinger, NN Makhova… - Russian Chemical …, 2020 - iopscience.iop.org
This review addresses some promising areas of chemistry of nitro compounds extensively
developed in recent years in Russia (particularly at the ND Zelinsky Institute of Organic …

Recent progress in the synthesis of isoxazoles

DX Duc, VC Dung - Current Organic Chemistry, 2021 - ingentaconnect.com
Isoxazole derivatives are aromatic five-membered ring heterocyclic compounds with one
oxygen atom and one nitrogen atom at adjacent positions. These compounds have a broad …

Synthetic Methods for Azaheterocyclic Phosphonates and Their Biological Activity: An Update 2004–2024

MC Mayorquín-Torres, A Simoens, E Bonneure… - Chemical …, 2024 - ACS Publications
The increasing importance of azaheterocyclic phosphonates in the agrochemical, synthetic,
and medicinal field has provoked an intense search in the development of synthetic routes …

Three-component Synthesis of 4-Arylidene-3-alkylisoxazol-5 (4H)-ones in the Presence of Potassium 2, 5-dioxoimidazolidin-1-ide

N Reihani, H Kiyani - Current Organic Chemistry, 2021 - ingentaconnect.com
An efficient synthesis of 4-arylidene-3-alkylisoxazole-5 (4H)-ones has been implemented via
the three-component cyclocondensation of aryl (heteroaryl) aldehydes with hydroxylamine …

The main directions and recent trends in the synthesis and use of isoxazoles

OB Bondarenko, NV Zyk - Chemistry of Heterocyclic Compounds, 2020 - Springer
This review summarizes the main directions and recent trends in the synthesis of isoxazoles,
and also provides examples of the use of isoxazoles as biologically active compounds in …

Straightforward access to the nitric oxide donor Azasydnone scaffold by cascade reactions of amines

ES Zhilin, DM Bystrov, IV Ananyev… - … A European Journal, 2019 - Wiley Online Library
A novel one‐pot cascade method for the assembly of valuable NO‐donor azasydnone
scaffold has been developed. The construction strategy involves a diazotization/azo …

Tick-borne flavivirus reproduction inhibitors based on isoxazole core linked with adamantane

DA Vasilenko, EV Dueva, LI Kozlovskaya, NA Zefirov… - Bioorganic …, 2019 - Elsevier
Infections caused by flaviviruses pose a huge threat for public health all over the world. The
search for therapeutically relevant compounds targeting tick-borne flaviviruses requires the …

A facile approach to bis (isoxazoles), promising ligands of the AMPA receptor

DA Vasilenko, KS Sadovnikov, KN Sedenkova… - Molecules, 2021 - mdpi.com
A convenient synthetic approach to novel functionalized bis (isoxazoles), the promising
bivalent ligands of the AMPA receptor, was elaborated. It was based on the heterocyclization …

5-Nitroisoxazoles in SNAr Reactions: A Novel Chemo- and Regioselective Approach to Isoxazole-Based Bivalent Ligands of AMPA Receptors

DA Vasilenko, NS Temnyakova, SE Dronov… - International Journal of …, 2023 - mdpi.com
An efficient regioselective approach to novel functionalized bis (isoxazoles) with a variety of
aromatic and aliphatic linkers was elaborated, based on the heterocyclization reaction of …