Alzheimer's disease: molecular aspects and treatment opportunities using herbal drugs

S Thakral, A Yadav, V Singh, M Kumar, P Kumar… - Ageing Research …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), also called senile dementia, is the most common
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …

[HTML][HTML] Fecal microbiota transplantation: A novel strategy for treating Alzheimer's disease

W Xiang, H Xiang, J Wang, Y Jiang, C Pan… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease is a common neurological disorder, which has become one of the major
factors affecting human health due to its serious impact on individuals, families and society …

[HTML][HTML] Molecular mechanism and potential therapeutic targets of necroptosis and ferroptosis in Alzheimer's disease

S Chavoshinezhad, E Beirami, E Izadpanah… - Biomedicine & …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), a neurodegenerative condition, is defined by
neurofibrillary tangles, amyloid plaques, and gradual cognitive decline. Regardless of the …

[HTML][HTML] Review of technological challenges in personalised medicine and early diagnosis of neurodegenerative disorders

C Domínguez-Fernández, J Egiguren-Ortiz… - International Journal of …, 2023 - mdpi.com
Neurodegenerative disorders are characterised by progressive neuron loss in specific brain
areas. The most common are Alzheimer's disease and Parkinson's disease; in both cases …

Protective function of StAR in amyloid-β accumulated hippocampal neurotoxicity and neurosteroidogenesis: Mechanistic insights into Alzheimer's disease

PR Manna, S Kshirsagar, JA Pradeepkiran… - … et Biophysica Acta (BBA …, 2023 - Elsevier
The steroidogenic acute regulatory (StAR) protein principally mediates steroid hormone
biosynthesis by governing the transport of intramitochondrial cholesterol. Neurosteroids …

Alzheimer's disease and its related dementias in us native americans: A major public health concern

U Sehar, J Kopel, PH Reddy - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) and Alzheimer's related dementias (ADRD) are growing public
health concerns in aged populations of all ethnic and racial groups. AD and ADRD are …

[HTML][HTML] The roles of the amyloid beta monomers in physiological and pathological conditions

TG Schreiner, OD Schreiner, M Adam, BO Popescu - Biomedicines, 2023 - mdpi.com
Amyloid beta peptide is an important biomarker in Alzheimer's disease, with the
amyloidogenic hypothesis as one of the central hypotheses trying to explain this type of …

Cellular response to β‐amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics

H Zhang, X Li, X Wang, J Xu, F Elefant… - Animal Models and …, 2023 - Wiley Online Library
Abstract β‐Amyloid (Aβ) is a specific pathological hallmark of Alzheimer's disease (AD).
Because of its neurotoxicity, AD patients exhibit multiple brain dysfunctions. Disease …

[HTML][HTML] Comprehensive understanding of Hispanic caregivers: focus on innovative methods and validations

U Sehar, P Rawat, M Choudhury… - Journal of …, 2023 - content.iospress.com
Alzheimer's disease (AD) and Alzheimer's disease-related disorders (ADRD) are late-onset,
age-related progressive neurodegenerative disorders, characterized by memory loss and …

[HTML][HTML] The rat brain transcriptome: from infancy to aging and sporadic Alzheimer's disease-like pathology

NA Stefanova, NG Kolosova - International Journal of Molecular Sciences, 2023 - mdpi.com
It has been suggested that functional traits of the adult brain—all of which are established
early in life—may affect the brain's susceptibility to Alzheimer's disease (AD). Results of our …