Nanomedicine greatly improves the efficiency in the delivery of antitumor drugs into the
tumor, but insufficient tumoral penetration impairs the therapeutic efficacy of most …

Tumor blood vessel formation is a key process for tumor expansion. Tumor vessels are
abnormal and differ from normal vessels in architecture and components. Besides oxygen …

Tumor blockade therapy is a promising penetration‐independent antitumor modality, which
effectively inhibits the exchange of nutrients, oxygen, and information between the tumor …

Hemorrhage is a potentially life-threatening emergency that can occur at any time or place.
Whether traumatic, congenital, surgical, disease-related, or drug-induced, bleeding can lead …

Interfacial nanobubbles (INBs) on a superhydrophobic surface has been proposed as a
solid cavitation agent for enhancing inertial cavitation dose and ultrasound contrast imaging …

Introduction Delivering sufficient therapeutics at the target site without off-target effects is a
major goal of drug delivery technology innovation. Among the established methods …

Rationale: Focused ultrasound-stimulated microbubbles have been shown to be capable of
inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed …

Therapeutic focused ultrasound in combination with encapsulated microbubbles is being
widely investigated for its ability to elicit bioeffects in the microvasculature, such as transient …

Anti-programmed cell death protein 1 (PD-1) therapy has shown promising efficacy in
hepatocellular carcinoma (HCC), but its response rates in advanced HCC are lower than …

Ultrasound-triggered microbubbles destruction leading to vascular shutdown have resulted
in preclinical studies in tumor growth delay or inhibition, lesion formation, radio-sensitization …