Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

C Ke, KMV Narayan, JCN Chan, P Jha… - Nature Reviews …, 2022 - nature.com
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

Diabetes in China: epidemiology and genetic risk factors and their clinical utility in personalized medication

C Hu, W Jia - Diabetes, 2018 - Am Diabetes Assoc
The incidence of type 2 diabetes (T2D) has rapidly increased over recent decades, and T2D
has become a leading public health challenge in China. Compared with European …

Developmental origins of health and disease: current knowledge and potential mechanisms

DJ Hoffman, RM Reynolds, DB Hardy - Nutrition reviews, 2017 - academic.oup.com
Epidemiologic and clinical research has provided a large body of evidence supporting the
developmental origins of health and disease (DOHaD), but there has been a relative dearth …

Severe malnutrition or famine exposure in childhood and cardiometabolic non-communicable disease later in life: a systematic review

K Grey, GB Gonzales, M Abera, N Lelijveld… - BMJ global …, 2021 - gh.bmj.com
Introduction Child malnutrition (undernutrition) and adult non-communicable diseases
(NCDs) are major global public health problems. While convincing evidence links prenatal …

Exposure to the Chinese famine of 1959–61 in early life and long-term health conditions: a systematic review and meta-analysis

C Li, LH Lumey - International journal of epidemiology, 2017 - academic.oup.com
Abstract Background Most Chinese people over 55 years old today have experienced the
Great Leap Forward Famine of 1959–61. Many reports suggested that the famine could …

DNA methylation in nonalcoholic fatty liver disease

J Hyun, Y Jung - International journal of molecular sciences, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a widespread hepatic disorder in the United
States and other Westernized countries. Nonalcoholic steatohepatitis (NASH), an advanced …

Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine

P Zimmet, Z Shi, A El-Osta, L Ji - Nature Reviews Endocrinology, 2018 - nature.com
The gene–environment interactions resulting from famine and the subsequent increased
intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current …

Association between famine exposure in early life and type 2 diabetes mellitus and hyperglycemia in adulthood: R esults from the C hina H ealth A nd R etirement L …

Y Sun, L Zhang, W Duan, X Meng, C Jia - Journal of diabetes, 2018 - Wiley Online Library
摘要背景一些研究已经表明生命早期饥荒暴露与成年后患2 型糖尿病(T2DM) 风险的相关性.
然而大多数中国大饥荒的相关研究只是以某个地区的人群作为研究对象, 并不是全国范围内的 …

Understanding health and social challenges for aging and long-term care in China

W Yang, B Wu, SY Tan, B Li, VWQ Lou… - Research on …, 2021 - journals.sagepub.com
The second King's College London Symposium on Ageing and Long-term Care in China
was convened from 4 to 5th July 2019 at King's College London in London. The aim of the …

[HTML][HTML] The famine exposure in early life and metabolic syndrome in adulthood

N Wang, X Wang, Q Li, B Han, Y Chen, C Zhu, Y Chen… - Clinical Nutrition, 2017 - Elsevier
Background & aims Epidemiologic studies have revealed that early-life conditions influence
later risk of chronic diseases. We aimed to explore whether exposure to Chinese famine …