Investigation of gene‐environment interactions (GxE) may provide important insights into the
gene regulatory framework in response to environmental factors of relevance for childhood …

We explored ancestry-related differences in the genetic architecture of whole-blood gene
expression using whole-genome and RNA sequencing data from 2,733 African Americans …

Type 2 T helper (TH2) cells are protective against parasitic worm infections but also
aggravate allergic inflammation. Although the role of dendritic cells (DCs) in TH2 cell …

Pulmonary function is an indicator of well-being, and pulmonary pathologies are the third
major cause of death worldwide. We analysed the UK Biobank genome-wide association …

Background The epigenetic mechanisms of asthma remain largely understudied in African
Americans and Hispanics/Latinos, two populations disproportionately affected by asthma …

Accumulating evidence suggests that an instant exposure to particulate matter (PM) may
elevate blood pressure (BP), where cell-adhesion regulatory genes may be involved in the …

Background and aim Systemic inflammation is one potential mechanism underlying
negative impact of air pollution on lung function. Levels of inflammation-related proteins …

Simple Summary African American (AA) populations experience higher lung cancer
incidence and mortality rates. We explore the role of long non-coding RNAs (lncRNAs) in …

Extract Technological advances spur scientific discovery. This is certainly true for
epigenomics, particularly DNA methylation (DNAm) analysis. Illumina's Infinium bead array …

Pulmonary function is an indicator of well-being, and pulmonary pathologies are the third
major cause of death worldwide. FEV1, FVC, and PEF are quantitively used to assess …