Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
Nanozymes: classification, catalytic mechanisms, activity regulation, and applications
Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …
widely used in industrial, medical, and biological fields, etc. Although promising, they often …
Chemical basis of reactive oxygen species reactivity and involvement in neurodegenerative diseases
F Collin - International journal of molecular sciences, 2019 - mdpi.com
Increasing numbers of individuals suffer from neurodegenerative diseases, which are
characterized by progressive loss of neurons. Oxidative stress, in particular, the …
characterized by progressive loss of neurons. Oxidative stress, in particular, the …
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis
Selenoproteins are rare proteins among all kingdoms of life containing the 21 st amino acid,
selenocysteine. Selenocysteine resembles cysteine, differing only by the substitution of …
selenocysteine. Selenocysteine resembles cysteine, differing only by the substitution of …
Metal–organic‐framework‐engineered enzyme‐mimetic catalysts
Nanomaterial‐based enzyme‐mimetic catalysts (Enz‐Cats) have received considerable
attention because of their optimized and enhanced catalytic performances and selectivities …
attention because of their optimized and enhanced catalytic performances and selectivities …
Nanozyme-involved biomimetic cascade catalysis for biomedical applications
Enzyme cascade reactions in biological systems can effectively improve the catalytic
performances owing to their high local concentration, efficient mass transfer and reduced …
performances owing to their high local concentration, efficient mass transfer and reduced …
Biochemistry of peroxynitrite and protein tyrosine nitration
G Ferrer-Sueta, N Campolo, M Trujillo… - Chemical …, 2018 - ACS Publications
Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …
Enzyme mimics for engineered biomimetic cascade nanoreactors: mechanism, applications, and prospects
Multiple enzyme‐driven biological catalytic cascades occur in living organisms, guiding
highly efficient and selective transformations of substrates. Inspired by the merits of these …
highly efficient and selective transformations of substrates. Inspired by the merits of these …
Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants
B Poljsak, D Šuput, I Milisav - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Free radical damage is linked to formation of many degenerative diseases, including cancer,
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …
Oxidative stress in rheumatoid arthritis: What the future might hold regarding novel biomarkers and add‐on therapies
LJS Fonseca, V Nunes-Souza… - Oxidative medicine …, 2019 - Wiley Online Library
Numerous rheumatologic autoimmune diseases, among which rheumatoid arthritis, are
chronic inflammatory diseases capable of inducing multiple cumulative articular and extra …
chronic inflammatory diseases capable of inducing multiple cumulative articular and extra …