Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome
JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …
Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management
JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …
The pathogenesis of the antiphospholipid syndrome
B Giannakopoulos, SA Krilis - New England Journal of Medicine, 2013 - Mass Medical Soc
The antiphospholipid syndrome is a prothrombotic disorder associated with autoantibodies.
It is associated with obstetrical complications (mainly spontaneous abortion) as well as …
It is associated with obstetrical complications (mainly spontaneous abortion) as well as …
Pathogenesis, diagnosis and management of obstetric antiphospholipid syndrome: a comprehensive review
J Alijotas-Reig, E Esteve-Valverde… - Journal of clinical …, 2022 - mdpi.com
Antiphospholipid syndrome is an autoimmune disorder characterized by vascular
thrombosis and/or pregnancy morbidity associated with persistent antiphospholipid antibody …
thrombosis and/or pregnancy morbidity associated with persistent antiphospholipid antibody …
Endothelium—role in regulation of coagulation and inflammation
VWM van Hinsbergh - Seminars in immunopathology, 2012 - Springer
By its strategic position at the interface between blood and tissues, endothelial cells control
blood fluidity and continued tissue perfusion while simultaneously they direct inflammatory …
blood fluidity and continued tissue perfusion while simultaneously they direct inflammatory …
Endothelial cell–activating antibodies in COVID‐19
H Shi, Y Zuo, S Navaz, A Harbaugh… - Arthritis & …, 2022 - Wiley Online Library
Objective While endothelial dysfunction has been implicated in the widespread
thromboinflammatory complications of COVID‐19, the upstream mediators of …
thromboinflammatory complications of COVID‐19, the upstream mediators of …
Pathogenesis of antiphospholipid syndrome: understanding the antibodies
PL Meroni, MO Borghi, E Raschi… - Nature Reviews …, 2011 - nature.com
Antiphospholipid antibodies (aPL) are both diagnostic markers for, and pathogenic drivers
of, antiphospholipid syndrome (APS). Although the presence of aPL is a necessary pre …
of, antiphospholipid syndrome (APS). Although the presence of aPL is a necessary pre …
Inhibition of the mTORC pathway in the antiphospholipid syndrome
G Canaud, F Bienaimé, F Tabarin… - … England Journal of …, 2014 - Mass Medical Soc
Background Although thrombosis is considered the cardinal feature of the antiphospholipid
syndrome, chronic vascular lesions are common, particularly in patients with life-threatening …
syndrome, chronic vascular lesions are common, particularly in patients with life-threatening …
Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics
MT Corban, A Duarte-Garcia, RD McBane… - Journal of the American …, 2017 - jacc.org
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …
Microvascular thrombosis: experimental and clinical implications
MA Bray, SE Sartain, J Gollamudi, RE Rumbaut - Translational Research, 2020 - Elsevier
A significant amount of clinical and research interest in thrombosis is focused on large
vessels (eg, stroke, myocardial infarction, deep venous thrombosis, etc.); however …
vessels (eg, stroke, myocardial infarction, deep venous thrombosis, etc.); however …