Pulmonary hypertension: Linking inflammation and pulmonary arterial stiffening
SF Liu, N Nambiar Veetil, Q Li… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …
and ultimately leads to right heart failure as the predominant cause of morbidity and …
Inflammation and immunity in the pathogenesis of hypoxic pulmonary hypertension
Y Ye, Q Xu, T Wuren - Frontiers in Immunology, 2023 - frontiersin.org
Hypoxic pulmonary hypertension (HPH) is a complicated vascular disorder characterized by
diverse mechanisms that lead to elevated blood pressure in pulmonary circulation. Recent …
diverse mechanisms that lead to elevated blood pressure in pulmonary circulation. Recent …
Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis
Y Tang, C Qian, Y Zhou, C Yu, M Song, T Zhang, X Min… - IScience, 2023 - cell.com
Platelets have been widely recognized as a bona fide mediator of malignant diseases, and
they play significant roles in influencing various aspects of tumor progression. Paracrine …
they play significant roles in influencing various aspects of tumor progression. Paracrine …
Calculated inflammatory markers derived from complete blood count results, along with routine laboratory and clinical data, predict treatment failure of acute peritonitis …
D Zhou, H Yang, L Zeng, W Yang, F Guo, W Cui… - Renal …, 2023 - Taylor & Francis
Abstract Background & Aims Complete blood count (CBC)-derived inflammatory markers are
predictive biomarkers for the prognosis of many diseases. However, there was no study on …
predictive biomarkers for the prognosis of many diseases. However, there was no study on …
[HTML][HTML] CC chemokines modulate immune responses in pulmonary hypertension
Q Yan, S Liu, Y Sun, C Chen, Y Yang… - Journal of Advanced …, 2024 - ncbi.nlm.nih.gov
Background Pulmonary hypertension (PH) represents a progressive condition characterized
by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and …
by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and …
Coagulation and fibrinolysis in obstructive sleep apnoea
A Bikov, M Meszaros, EI Schwarz - International Journal of Molecular …, 2021 - mdpi.com
Obstructive sleep apnoea (OSA) is a common disease which is characterised by repetitive
collapse of the upper airways during sleep resulting in chronic intermittent hypoxaemia and …
collapse of the upper airways during sleep resulting in chronic intermittent hypoxaemia and …
[HTML][HTML] Therapeutic potential for targeting Annexin A1 in fibrotic diseases
Z Yan, X Cheng, T Wang, X Hong, G Shao, C Fu - Genes & Diseases, 2022 - Elsevier
Annexin A1, a well-known endogenous anti-inflammatory mediator, plays a critical role in a
variety of pathological processes. Fibrosis is described by a failure of tissue regeneration …
variety of pathological processes. Fibrosis is described by a failure of tissue regeneration …
[HTML][HTML] Pyroptosis, apoptosis, necroptosis and endoplasmic reticulum stress in pulmonary hypertension
Q Yan, S Liu, Y Sun, C Chen, Y Yang, S Yang… - Journal of Advanced …, 2023 - Elsevier
Background Pulmonary hypertension (PH) represents a progressive condition characterized
by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and …
by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and …
Lung regeneration: diverse cell types and the therapeutic potential
Lung tissue has a certain regenerative ability and triggers repair procedures after injury.
Under controllable conditions, lung tissue can restore normal structure and function …
Under controllable conditions, lung tissue can restore normal structure and function …
Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome
The transcriptional response to hypoxia is temporally regulated, yet the molecular
underpinnings and physiological implications are unknown. We examined the roles of …
underpinnings and physiological implications are unknown. We examined the roles of …