[HTML][HTML] Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
[HTML][HTML] Programming assembly of biomimetic exosomes: an emerging theranostic nanomedicine platform
X Xu, L Xu, C Wen, J Xia, Y Zhang, Y Liang - Materials Today Bio, 2023 - Elsevier
Exosomes have emerged as a promising cell-free therapeutic approach. However,
challenges in large-scale production, quality control, and heterogeneity must be overcome …
challenges in large-scale production, quality control, and heterogeneity must be overcome …
Cell‐specific targeting of extracellular vesicles through engineering the glycocalyx
W Zheng, R He, X Liang, S Roudi, J Bost… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are promising carriers for the delivery of a variety of chemical
and biological drugs. However, their efficacy is limited by the lack of cellular specificity …
and biological drugs. However, their efficacy is limited by the lack of cellular specificity …
[HTML][HTML] Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles
Extracellular vesicles (EVs) are gaining ground as next-generation drug delivery modalities.
Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability …
Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability …
[HTML][HTML] Application of nano-delivery systems in lymph nodes for tumor immunotherapy
Y Xia, S Fu, Q Ma, Y Liu, N Zhang - Nano-micro letters, 2023 - Springer
Immunotherapy has become a promising research “hotspot” in cancer treatment.“Soldier”
immune cells are not uniform throughout the body; they accumulate mostly in the immune …
immune cells are not uniform throughout the body; they accumulate mostly in the immune …
[HTML][HTML] Surface display of functional moieties on extracellular vesicles using lipid anchors
W Zheng, M Schürz, RJ Wiklander, O Gustafsson… - Journal of Controlled …, 2023 - Elsevier
Extracellular vesicles (EVs) are efficient natural vehicles for intercellular communication and
are under extensive investigation for the delivery of diverse therapeutics including small …
are under extensive investigation for the delivery of diverse therapeutics including small …
[HTML][HTML] Small extracellular vesicles: a novel drug delivery system for neurodegenerative disorders
R Pan, D Chen, L Hou, R Hu, Z Jiao - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Neurodegenerative diseases (NDs) have a slow onset and are usually detected late during
disease. NDs are often difficult to cure due to the presence of the blood–brain barrier (BBB) …
disease. NDs are often difficult to cure due to the presence of the blood–brain barrier (BBB) …
[HTML][HTML] Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent
Extracellular vesicles (EVs) derived from mesenchymal stem cells are promising
nanotherapeutics in liver diseases due to their regenerative and immunomodulatory …
nanotherapeutics in liver diseases due to their regenerative and immunomodulatory …
A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series,“Therapeutic advances with native and engineered human extracellular …
Abstract The International Society for Cell & Gene Therapy Scientific Signature Series event
“Therapeutic Advances With Native and Engineered Human EVs” took place as part of the …
“Therapeutic Advances With Native and Engineered Human EVs” took place as part of the …
Advances in therapeutic applications of extracellular vesicles
Y Zhang, Y Dou, Y Liu, M Di, H Bian… - International Journal of …, 2023 - Taylor & Francis
Extracellular vesicles (EVs) are nanoscale bilayer phospholipid membrane vesicles
released by cells. Contained large molecules such as nucleic acid, protein, and lipid, EVs …
released by cells. Contained large molecules such as nucleic acid, protein, and lipid, EVs …