Recurrent miscarriage (RM) occurs in 1–3% of couples aiming at childbirth. Due to
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …

Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …

According to current estimates, infertility affects one in four couples trying to conceive.
Primary or secondary infertility can be due either to both partners or only to the man or the …

Mitochondrial biology has become an area of intense research owing to the unique
physiology of the organelle and its role in several types of cancers and other disorders. It …

Sperm mitochondrial dysfunction causes the generation of an insufficient amount of energy
needed for sperm motility. This will affect sperm fertilization capacity, and thus, most …

Mitochondrial DNA (mtDNA) of oocyte is critical for its function, embryo quality and
development. Analysis of complete mtDNA of 49 oocytes and 18 blastocysts from 67 females …

In-vitro studies with different Fanconi anemia (FA) cell lines and FANC gene silenced cell
lines indicating involvement of mitochondria function in pathogenesis of FA have been …

Buffalo physiology intricately balances energy, profoundly influencing health, productivity,
and reproduction. This study explores nuclear-mitochondrial crosstalk, revealing OXPHOS …

Cases with three or more consecutive spontaneous abortions before the 20th week of
gestation are termed as recurrent pregnancy loss (RPL). Problems in implantation of the …

Several genetic factors are involved with recurrent pregnancy loss (RPL). However, few
attempts have been made to associate mitochondrial DNA (mtDNA) variations with RPL …