Research advances defining how zinc is transported into and out of cells and organelles
have increased exponentially within the past five years. Research has progressed through …

Two families of zinc (Zn2+) transporters are involved in zinc homeostasis in the body, SLC30
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …

In your complex and dynamic field, it can be a struggle to continually integrate the latest
scientific and clinical information into your everyday patient care. The 11th Edition of this …

Aims/hypothesis To investigate the longitudinal relationship between the gut microbiome,
circulating short chain fatty acids (SCFAs) and intestinal permeability in children with islet …

Zinc (Zn) is a vital element. It plays indispensable roles in multifarious cellular processes,
affecting the expression and activity of a variety of molecules, including transcription factors …

Context: Autoantibodies that are reactive to islet antigens are present at the time of
diagnosis in most patients with type 1 diabetes. Additionally, approximately 10% of …

Abstract Type 1 diabetes (T1DM) is an autoimmune disease with aberrant immune
responses to specific β-cell autoantigens, resulting in insulin deficiency. Children and …

The incidence of type 1 diabetes is increasing and this may double the burden of disease in
our youngest by 2020. The recent increase in incidence is mostly happening in the very …

OBJECTIVE To describe an etiologic approach to classification of diabetes types in youth
based on the 1997 American Diabetes Association (ADA) framework, using data from the …

OBJECTIVE The first-appearing β-cell autoantibody has been shown to influence risk of type
1 diabetes (T1D). Here, we assessed the risk of autoantibody spreading to the second …